Add to ORKGThe invention relates to novel piperazine compounds; to processes for their preparation; to pharmaceutical composi tions containing the compounds; and to the use of the compounds in therapy to treat diseases for which blocking the Ca 2.2 calcium channels is beneficial, i.e. in particular to treat pain
The invention provides novel compounds based on piperazinylpyrimidine derivatives to be used as prot...
The piperazine derivatives have been shown to inhibit human acetylcholinesterase. Virtual screening ...
A series of new 1-heteroaryl piperidinecarboxamide and piperazinylurea derivatives was synthesized a...
The present invention relates to novel piperazine derivatives; to processes for their preparation; t...
The invention relates to an agent for the medicamentous treatment of acute and chronic pain, in part...
AbstractWe previously reported the small organic N-type calcium channel blocker NP078585 that while ...
ABSTRACT: Low-voltage-activated (T-type) calcium chan-nels are important regulators of the transmiss...
The present invention relates to piperazinone compounds, pharmaceutical compositions containing thos...
A novel series of CXCR4 antagonists with piperidinyl and piperazinyl alkylamine side chains designed...
Aim: Hydralazine has led to the synthesis of phthalazinone derivatives which induce vasorelaxation. ...
The treatment of neuropathic pain is one of the urgent unmet medical needs and T-type calcium channe...
Doctor of PhilosophyDepartment of ChemistryDuy H. HuaThree research projects are described in this d...
Highly selective Cav2.2 voltage-gated calcium channel (VGCC) inhibitors have emerged as a new class ...
Abstract Background Both T-type calcium channels and cannabinoid receptors modulate signalling in th...
In this work, a series of arylpiperazine derivatives were synthesized and screened by in vivo pharma...
The invention provides novel compounds based on piperazinylpyrimidine derivatives to be used as prot...
The piperazine derivatives have been shown to inhibit human acetylcholinesterase. Virtual screening ...
A series of new 1-heteroaryl piperidinecarboxamide and piperazinylurea derivatives was synthesized a...
The present invention relates to novel piperazine derivatives; to processes for their preparation; t...
The invention relates to an agent for the medicamentous treatment of acute and chronic pain, in part...
AbstractWe previously reported the small organic N-type calcium channel blocker NP078585 that while ...
ABSTRACT: Low-voltage-activated (T-type) calcium chan-nels are important regulators of the transmiss...
The present invention relates to piperazinone compounds, pharmaceutical compositions containing thos...
A novel series of CXCR4 antagonists with piperidinyl and piperazinyl alkylamine side chains designed...
Aim: Hydralazine has led to the synthesis of phthalazinone derivatives which induce vasorelaxation. ...
The treatment of neuropathic pain is one of the urgent unmet medical needs and T-type calcium channe...
Doctor of PhilosophyDepartment of ChemistryDuy H. HuaThree research projects are described in this d...
Highly selective Cav2.2 voltage-gated calcium channel (VGCC) inhibitors have emerged as a new class ...
Abstract Background Both T-type calcium channels and cannabinoid receptors modulate signalling in th...
In this work, a series of arylpiperazine derivatives were synthesized and screened by in vivo pharma...
The invention provides novel compounds based on piperazinylpyrimidine derivatives to be used as prot...
The piperazine derivatives have been shown to inhibit human acetylcholinesterase. Virtual screening ...
A series of new 1-heteroaryl piperidinecarboxamide and piperazinylurea derivatives was synthesized a...