Additional support for schizophrenia linkage on chromosomes 6 and 8: a multicenter study. Schizophrenia Linkage Collaborative Group for Chromosomes 3, 6 and 8
- Levinson, D. F.
- Wildenauer, D. B.
- Schwab, S. G.
- Albus, M.
- Hallmayer, J.
- Lerer, B.
- Maier, W.
- Blackwood, D.
- Muir, W.
- StClair, D.
- Morris, S.
- Moises, H. W.
- Yang, L.
- Kristbjarnarson, H.
- Helgason, T.
- Wiese, C.
- Collier, D. A.
- Holmans, Peter Alan
- Daniels, J.
- Rees, M.
- Asherson, P.
- Roberts, Q.
- Cardno, A.
- Arranz, M. J.
- Vallada, H.
- McGuffin, D.
- Owen, Michael John
- Pulver, A. E.
- Antonarakis, S. E.
- Babb, R.
- Blouin, J. L.
- DeMarchi, N.
- Dombroski, B.
- Housman, D.
- Karayiorgou, M.
- Ott, J.
- Kasch, L.
- Kazazian, H.
- Lasseter, V. K.
- Loetscher, E.
- Luebbert, H.
- Nestadt, G.
- Ton, C.
- Wolyniec, P. S.
- Laurent, C.
- deChaldee, M.
- Thibaut, F.
- Jay, M.
- Samolyk, D.
- Petit, M.
- Campion, D.
- Mallet, J.
- Straub, R. E.
- MacLean, C. J.
- Easter, S. M.
- ONeill, F. A.
- Walsh, D.
- Kendler, K. S.
- Gejman, P. V.
- Cao, Q. H.
- Gershon, E.
- Badner, J.
- Beshah, E.
- Zhang, J.
- Riley, B. P.
- Rajagopalan, S.
- MogudiCarter, M.
- Jenkins, T.
- Williamson, R.
- DeLisi, L. E.
- Garner, C.
- Kelly, M.
- LeDuc, C.
- Cardon, L.
- Lichter, J.
- Harris, T.
- Loftus, J.
- Shields, G.
- Comasi, M.
- Vita, A.
- Smith, A.
- Dann, J.
- Joslyn, G.
- Gurling, H.
- Kalsi, G.
- Brynjolfsson, J.
- Curtis, D.
- Sigmundsson, T.
- Butler, R.
- Read, T.
- Murphy, P.
- Chen, A. C. H.
- Petursson, H.
- Byerley, B.
- Hoff, M.
- Holik, J.
- Nancarrow, D. J.
- Crowe, R. R.
- Andreasen, N.
- Silverman, J. M.
- Mohs, R. C.
- Siever, L. J.
- Endicott, J.
- Sharpe, L.
- Walters, M. K.
- Lennon, D. P.
- Hayward, N. K.
- Sandkuijl, L. A.
- Mowry, B. J.
- Aschauer, H. N.
- Meszaros, K.
- Lenzinger, E.
- Fuchs, K.
- Heiden, A. M.
- Kruglyak, L.
- Daly, M. J.
- Matise, T. C.
DOIAbstract
In response to reported schizophrenia linkage findings on chromosomes 3, 6 and 8, fourteen research groups genotyped 14 microsatellite markers in an unbiased, collaborative (New) sample of 403-567 informative pedigrees per marker, and in the Original sample which produced each finding (the Johns Hopkins University sample of 46-52 informative pedigrees for chromosomes 3 and 8, and the Medical College of Virginia sample of 156-191 informative pedigrees for chromosome 6). Primary planned analyses (New sample) were two-point heterogeneity lod score (lod2) tests (dominant and recessive affected-only models), and multipoint affected sibling pair (ASP) analysis, with a narrow diagnostic model (DSM-IIIR schizophrenia and schizoaffective disorders)....
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