Add to ORKGCalcium is a ubiquitous signalling molecule, known to control a vast array of cellular processes. In order to retain stimulus fidelity, the cell encodes the increases in intracellular calcium in the form of oscillations that are regulated both temporally and spatially. Here, we review recent work, using the pancreatic acinar cell as a model system, on the mechanisms employed to generate and modulate cytosolic Ca(2+) signals, and the technical advances that have made these studies possible
In the past decade, there have been remarkable advances in our understanding of the calcium messenge...
In the past decade, there have been remarkable advances in our understanding of the calcium messenge...
The agonists acetylcholine (ACh) and cholecystokinin (CCK) evoke oscillating cytosolic Ca2+ signals ...
Calcium is a ubiquitous signalling molecule, known to control a vast array of cellular processes. In...
Calcium is a ubiquitous signalling molecule, known to control a vast array of cellular processes. In...
Cytosolic calcium signals are produced by suddenly increasing the concentration of free calcium ions...
The pancreatic acinar cell is a classical model for studies of secretion and signal transduction mec...
AbstractThe changes in cytosolic free calcium concentration ([Ca2+]i) were monitored (fura-2) in sin...
A calcium signal is a sudden increase in the concentration of calcium ions (Ca2+) in the cytosol. Su...
A calcium signal is a sudden increase in the concentration of calcium ions (Ca2+) in the cytosol. Su...
The pancreatic acinar unit is a classical example of a polarized tissue. Even in isolation, these ce...
The pancreatic acinar unit is a classical example of a polarized tissue. Even in isolation, these ce...
The pancreatic acinar unit is a classical example of a polarized tissue. Even in isolation, these ce...
The pancreatic acinar unit is a classical example of a polarized tissue. Even in isolation, these ce...
The pancreatic acinar unit is a classical example of a polarized tissue. Even in isolation, these ce...
In the past decade, there have been remarkable advances in our understanding of the calcium messenge...
In the past decade, there have been remarkable advances in our understanding of the calcium messenge...
The agonists acetylcholine (ACh) and cholecystokinin (CCK) evoke oscillating cytosolic Ca2+ signals ...
Calcium is a ubiquitous signalling molecule, known to control a vast array of cellular processes. In...
Calcium is a ubiquitous signalling molecule, known to control a vast array of cellular processes. In...
Cytosolic calcium signals are produced by suddenly increasing the concentration of free calcium ions...
The pancreatic acinar cell is a classical model for studies of secretion and signal transduction mec...
AbstractThe changes in cytosolic free calcium concentration ([Ca2+]i) were monitored (fura-2) in sin...
A calcium signal is a sudden increase in the concentration of calcium ions (Ca2+) in the cytosol. Su...
A calcium signal is a sudden increase in the concentration of calcium ions (Ca2+) in the cytosol. Su...
The pancreatic acinar unit is a classical example of a polarized tissue. Even in isolation, these ce...
The pancreatic acinar unit is a classical example of a polarized tissue. Even in isolation, these ce...
The pancreatic acinar unit is a classical example of a polarized tissue. Even in isolation, these ce...
The pancreatic acinar unit is a classical example of a polarized tissue. Even in isolation, these ce...
The pancreatic acinar unit is a classical example of a polarized tissue. Even in isolation, these ce...
In the past decade, there have been remarkable advances in our understanding of the calcium messenge...
In the past decade, there have been remarkable advances in our understanding of the calcium messenge...
The agonists acetylcholine (ACh) and cholecystokinin (CCK) evoke oscillating cytosolic Ca2+ signals ...