Light-Oxygen-Voltage (LOV) domains are flavoproteins that are part of photoreceptors found in plants, prokaryotes and algae. LOV domains act as biological switches in response sensors to oxygen, redox potential or light, making them ideal for use as an optogenetics tool. The protein-switch is activated by formation of a covalent adduct between the flavin cofactor and an internal cysteine residue, causing changes in the hydrogen bonding network in the core of the protein. This results in a conformational change in the LOV domain leading to undocking of an amphiphilic helix that is generally coupled to a catalytic or transcriptional activation domain. In this investigation the LOV2 domain of phototropin 1 from Avena sativa has been modified ...
LOV proteins are UVA/Blue light photoreceptors employing LOV (light, oxygen, voltage) domains as pho...
Optogenetics is an emerging field that combines optical and genetic approaches to non-invasively int...
Photosensing LOV (Light, Oxygen, Voltage) domains detect and respond to UVA/Blue (BL) light by formi...
Light-Oxygen-Voltage (LOV) domains are flavoproteins that are part of photoreceptors found in plants...
LOV domains act as biomolecular sensors for light, oxygen or the environment's redox potential. Conf...
Cellular optogenetic switches, a novel class of biological tools, have improved our understanding of...
Photocontrol of functional peptides is a powerful tool for spatial and temporal control of cell sign...
SummaryPhotocontrol of functional peptides is a powerful tool for spatial and temporal control of ce...
<div><p>Light-oxygen-voltage (LOV) domains function as blue light-inducible molecular switches. The ...
Light-oxygen-voltage (LOV) domains function as blue light-inducible molecular switches. The photosen...
<p>(A) The second light-oxygen-voltage (LOV) domain derived from <i>Avena sativa</i> phototropin 1 (...
Algae, plants, bacteria, and fungi contain flavin-binding light-oxygen-voltage (LOV) domains that fu...
Light-activated protein domains provide a convenient, modular, and genetically encodable sensor for ...
Light-, Oxygen- and Votlage- (LOV) domains are blue-light activated photoreceptors that control vari...
The rational engineering of photosensor proteins underpins the field of optogenetics, in which light...
LOV proteins are UVA/Blue light photoreceptors employing LOV (light, oxygen, voltage) domains as pho...
Optogenetics is an emerging field that combines optical and genetic approaches to non-invasively int...
Photosensing LOV (Light, Oxygen, Voltage) domains detect and respond to UVA/Blue (BL) light by formi...
Light-Oxygen-Voltage (LOV) domains are flavoproteins that are part of photoreceptors found in plants...
LOV domains act as biomolecular sensors for light, oxygen or the environment's redox potential. Conf...
Cellular optogenetic switches, a novel class of biological tools, have improved our understanding of...
Photocontrol of functional peptides is a powerful tool for spatial and temporal control of cell sign...
SummaryPhotocontrol of functional peptides is a powerful tool for spatial and temporal control of ce...
<div><p>Light-oxygen-voltage (LOV) domains function as blue light-inducible molecular switches. The ...
Light-oxygen-voltage (LOV) domains function as blue light-inducible molecular switches. The photosen...
<p>(A) The second light-oxygen-voltage (LOV) domain derived from <i>Avena sativa</i> phototropin 1 (...
Algae, plants, bacteria, and fungi contain flavin-binding light-oxygen-voltage (LOV) domains that fu...
Light-activated protein domains provide a convenient, modular, and genetically encodable sensor for ...
Light-, Oxygen- and Votlage- (LOV) domains are blue-light activated photoreceptors that control vari...
The rational engineering of photosensor proteins underpins the field of optogenetics, in which light...
LOV proteins are UVA/Blue light photoreceptors employing LOV (light, oxygen, voltage) domains as pho...
Optogenetics is an emerging field that combines optical and genetic approaches to non-invasively int...
Photosensing LOV (Light, Oxygen, Voltage) domains detect and respond to UVA/Blue (BL) light by formi...