Darier's Disease (DD) is a rare autosomal dominantly inherited skin disorder in which co-occurrence of neuropsychiatric abnormalities has been frequently reported by dermatologists. The disease is caused by mutations in a single gene, ATP2A2, which maps to 12q23-q24.1 and is expressed in the skin and brain. This gene encodes SERCA2 (sarco/endoplasmic reticulum Ca 2+ ATPase isoform 2), a calcium pump involved in intracellular calcium transport. This study aimed to conduct the first systematic investigation of the neuropsychiatric phenotype in DD, investigate possible genotype-phenotype correlations, and compare the neuropsychiatric features in DD individuals and their first-degree unaffected relatives. One hundred unrelated individuals with ...
Objectives Darier disease is an autosomal dominant skin disorder caused by mutations in the ATPase,...
Mutation analysis in the ATP2A2 gene had been performed in eight Hungarian patients with Darier's di...
Darier's disease is a rare autosomal dominant skin disorder in which there is abnormal adhesion betw...
Darier disease (DD) is an autosomal dominant skin disorder caused by mutations in ATP2A2 encoding th...
Darier Disease (DD) is an autosomal dominant skin disorder caused by mutations in ATP2A2 encoding th...
Background Darier disease (DD) is a rare autosomal dominantly inherited skin disorder in which co-o...
Darier's disease (DD) is a rare, dominantly inherited disorder that affects the skin producing a var...
Darier's disease (DD) is an autosomal dominant skin disorder characterized clinically by multiple ke...
Darier's disease (DD) is an autosomal dominant skin disorder characterized clinically by multiple ke...
Bipolar affective disorder is a genetically complex psychiatric disorder with a population prevalenc...
Background: Darier disease (DD) is a rare autosomal dominant condition characterized by skin lesio...
Darier's disease is a rare, inherited autosomal dominant skin disorder caused by a mutation in the s...
Darier disease is a rare and severe autosomal dominant skin disease characterised by malodorous kera...
Darier disease (DD) is a severe, inherited dermatological disorder with a characteristic clinical a...
Darier's disease is a rare autosomal dominantly inherited keratosis.1 We have previously reported a ...
Objectives Darier disease is an autosomal dominant skin disorder caused by mutations in the ATPase,...
Mutation analysis in the ATP2A2 gene had been performed in eight Hungarian patients with Darier's di...
Darier's disease is a rare autosomal dominant skin disorder in which there is abnormal adhesion betw...
Darier disease (DD) is an autosomal dominant skin disorder caused by mutations in ATP2A2 encoding th...
Darier Disease (DD) is an autosomal dominant skin disorder caused by mutations in ATP2A2 encoding th...
Background Darier disease (DD) is a rare autosomal dominantly inherited skin disorder in which co-o...
Darier's disease (DD) is a rare, dominantly inherited disorder that affects the skin producing a var...
Darier's disease (DD) is an autosomal dominant skin disorder characterized clinically by multiple ke...
Darier's disease (DD) is an autosomal dominant skin disorder characterized clinically by multiple ke...
Bipolar affective disorder is a genetically complex psychiatric disorder with a population prevalenc...
Background: Darier disease (DD) is a rare autosomal dominant condition characterized by skin lesio...
Darier's disease is a rare, inherited autosomal dominant skin disorder caused by a mutation in the s...
Darier disease is a rare and severe autosomal dominant skin disease characterised by malodorous kera...
Darier disease (DD) is a severe, inherited dermatological disorder with a characteristic clinical a...
Darier's disease is a rare autosomal dominantly inherited keratosis.1 We have previously reported a ...
Objectives Darier disease is an autosomal dominant skin disorder caused by mutations in the ATPase,...
Mutation analysis in the ATP2A2 gene had been performed in eight Hungarian patients with Darier's di...
Darier's disease is a rare autosomal dominant skin disorder in which there is abnormal adhesion betw...