Outcome of flow-gradient patterns of aortic stenosis after aortic valve replacement : an analysis of the PARTNER 2 trial and registry
- Dahou, Abdellaziz
- Rodés-Cabau, Josep
- Hahn, Rebecca T.
- Beaudoin, Jonathan
- Jaber, Wael A.
- Annabi, Mohamed Salah
- Asch, Federico M.
- Bernier, Mathieu
- Rodriguez, L. Leonardo
- Pibarot, Philippe
- Weissman, Neil J.
- Clavel, Marie-Annick
- Gertz, Zachary M.
- Ong, Géraldine
- Herrmann, Howard C.
- Salaun, Erwan
- Toubal, Oumhani
- Leipsic, Jonathon
- Blanke, Philipp
- Ridard, Carine
- Webb, John G. (John Graydon)
- Zhang, Yiran
- Alu, Maria C.
- Douglas, Pamela S.
- Makkar, Rajendra
- Miller, D. Craig
- Lindman, Brian R.
- Thourani, Vinod H.
- Leon, Martin B.
DOIAbstract
Background : Although aortic valve replacement is associated with a major benefit in high-gradient (HG) severe aortic stenosis (AS), the results in low-gradient (LG, mean gradient <40 mm Hg) AS are conflicting. LG severe AS may be subdivided in classical low-flow (left ventricular ejection fraction <50%) and LG (CLF-LG); paradoxical low-flow (left ventricular ejection fraction ≥50% but stroke volume index <35 mL/m2) and LG; and normal-flow (left ventricular ejection fraction ≥50% and stroke volume index ≥35 mL/m2) and LG. The primary objective is to determine in the PARTNER 2 trial (The Placement of Aortic Transcatheter Valves) and registry the outcomes after aortic valve replacement of the 4 flow-gradient groups. Methods : A total of 3511...
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