Electrochemical Preparation of Polyaniline- Supported Cu-CuO Core-Shell on 316L Stainless Steel Electrodes for Nonenzymatic Glucose Sensor

In this article, we reported the elaboration of a nonenzymatic glucose sensor based on the polyaniline-supported Cu-CuO core-shell structure prepared on the 316L stainless steel electrode by electrochemical methods. In the first step, polyaniline (PANI) film was electrodeposited on the 316L substrate from a solution of 0.1 M aniline and 0.5 M sulfuric acid in absolute ethanol by the cyclic voltammetry (CV) method. In the second step, the copper particles were electrodeposited on the PANI film from CuCl2·2H2O 0.01 M precursor prepared in a KCl 0.1 M solution by the CV method. In the third step, Cu particles were partially oxidized to CuO by the CV method in a NaOH 0.1 M electrolyte to form a Cu-CuO core-shell structure supported on the PANI film. The as-prepared electrode (Cu-CuO/PANI/316L) was used to detect glucose in a NaOH 0.1 M solution. The Cu-CuO/PANI/316L sensor exhibited a linear range of 0.1–5 mM (R2 = 0.995) with a detection limit of 0.1 mM (S/N = 3) and high sensitivity of (25.71 mA·mM−1·cm−2). In addition, no significant interference was observed from sucrose, maltose, lactose, and ascorbic acid. The results showed that the polyaniline-supported Cu-CuO core-shell structure has the potential to be applied as an electrode material for the nonenzymatic glucose sensor