The ability of viral particles to directly spread cell to cell within the airways without particle release is considered to be highly advantageous to many respiratory viruses. Our previous studies in well-differentiated, primary human airway epithelial cells suggest that measles virus (MeV) spreads cell to cell by eliciting the formation of intercellular membrane pores. Based on a newly generated ribonucleoprotein complex (RNP) “tracker” virus, we document by live-cell microscopy that MeV RNPs move along F-actin rings before entering a new cell. Thus, rather than diffusing through the cytoplasm of a newly infected columnar cell, RNPs take advantage of the cytoskeletal infrastructure to rapidly spread laterally across the human airway epithe...
Nonsegmented negative-strand RNA viruses, including measles virus (MeV), a member of the Paramyxovir...
ABSTRACT Human metapneumovirus (HMPV) can spread between cells through budding of virus particles or...
Transmission of measles virus (MV) from dendritic to airway epithelial cells is considered as crucia...
The discovery that measles virus (MV) uses the adherens junction protein nectin-4 as its epithelial ...
Measles virus (MV) is typically spread by aerosol droplets and enters via the respiratory tract. The...
<p>A) The canonical route of virus spread involves the release of completely assembled viral particl...
Measles virus (MV), one of the most contagious viruses infecting humans, causes a systemic infection...
Human metapneumovirus (HMPV) is a leading cause of respiratory tract infections worldwide across all...
Paramyxovirus spread generally involves assembly of individual viral particles which then infect tar...
Gene therapy for cystic fibrosis (CF) lung disease requires efficient gene transfer to airway epithe...
International audienceAfter the contagion measles virus (MV) crosses the respiratory epithelium with...
textabstractThe lymphotropic and myelotropic nature of wild-type measles virus (wt-MV) is well recog...
2013-12-05Measles virus, enveloped RNA virus, infects lungs, airways, lymphocytes and multiple organ...
AbstractThe initial site of virus replication during measles infection is in the epithelial cells of...
Measles remains a leading vaccine-preventable cause of child mortality globally. Although a live-att...
Nonsegmented negative-strand RNA viruses, including measles virus (MeV), a member of the Paramyxovir...
ABSTRACT Human metapneumovirus (HMPV) can spread between cells through budding of virus particles or...
Transmission of measles virus (MV) from dendritic to airway epithelial cells is considered as crucia...
The discovery that measles virus (MV) uses the adherens junction protein nectin-4 as its epithelial ...
Measles virus (MV) is typically spread by aerosol droplets and enters via the respiratory tract. The...
<p>A) The canonical route of virus spread involves the release of completely assembled viral particl...
Measles virus (MV), one of the most contagious viruses infecting humans, causes a systemic infection...
Human metapneumovirus (HMPV) is a leading cause of respiratory tract infections worldwide across all...
Paramyxovirus spread generally involves assembly of individual viral particles which then infect tar...
Gene therapy for cystic fibrosis (CF) lung disease requires efficient gene transfer to airway epithe...
International audienceAfter the contagion measles virus (MV) crosses the respiratory epithelium with...
textabstractThe lymphotropic and myelotropic nature of wild-type measles virus (wt-MV) is well recog...
2013-12-05Measles virus, enveloped RNA virus, infects lungs, airways, lymphocytes and multiple organ...
AbstractThe initial site of virus replication during measles infection is in the epithelial cells of...
Measles remains a leading vaccine-preventable cause of child mortality globally. Although a live-att...
Nonsegmented negative-strand RNA viruses, including measles virus (MeV), a member of the Paramyxovir...
ABSTRACT Human metapneumovirus (HMPV) can spread between cells through budding of virus particles or...
Transmission of measles virus (MV) from dendritic to airway epithelial cells is considered as crucia...