Polarization sensitive optical coherence tomography of melanin provides tissue inherent contrast based on depolarization
- Baumann, Bernhard
- Baumann, Stefan O.
- Konegger, Thomas
- Pircher, Michael
- Götzinger, Erich
- Sattmann, Harald
- Litschauer, Marco
- Hitzenberger, Christoph K.
Publication date
February 2010
DOI Publisher
SPIE-Intl Soc Optical Eng Journal
issn:0277-786X Citation count (estimate)
4Abstract
Polarization sensitive optical coherence tomography (PS-OCT) was used to investigate the polarization properties of melanin. Measurements in samples with varying melanin concentrations revealed polarization scrambling, i.e. depolarization. The results indicate that the depolarizing appearance of pigmented structures like, for instance, the retinal pigment epithelium (RPE) is likely to be caused by the melanin granules contained in these cells.Austrian Science Fund (FWF grants P19624-B02 and P19751-N20
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