Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a devastating skin blistering disease caused by mutations in the gene encoding type VII collagen (C7), leading to epidermal fragility, trauma-induced blistering, and long term, hard-to-heal wounds. Fibrosis develops rapidly in RDEB skin and contributes to both chronic wounds, which emerge after cycles of repetitive wound and scar formation, and squamous cell carcinoma—the single biggest cause of death in this patient group. The molecular pathways disrupted in a broad spectrum of fibrotic disease are also disrupted in RDEB, and squamous cell carcinomas arising in RDEB are thus far molecularly indistinct from other sub-types of aggressive squamous cell carcinoma (SCC). Collectively these da...
Genetic loss of collagen VII causes recessive dystrophic epidermolysis bullosa (RDEB)—a severe skin ...
University of Minnesota Ph.D. dissertation. 2021. Major: Molecular, Cellular, Developmental Biology ...
Context: Connective tissue cells include fibroblasts, chondrocytes, adipocyte, and osteocytes. These...
The heritable blistering disorder recessive dystrophic epidermolysis bullosa (RDEB) is a devastating...
BACKGROUND: Poorly healing wounds are one of the major complications in patients suffering from rece...
Mención Internacional en el título de doctorGenodermatoses are rare inherited skin diseases, mostly ...
2014-10-20Dystrophic epidermolysis bullosa (DEB) is a family of rare inherited mechano-bullous disor...
Inflammation is known to play a critical role in all stages of tumorigenesis; however, less is known...
Inflammation is known to play a critical role in all stages of tumorigenesis; however, less is known...
Background: Recessive dystrophic epidermolysis bullosa (RDEB) is an inherited blistering disease cau...
Inflammation is known to play a critical role in all stages of tumorigenesis; however, less is known...
Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a devastating skin blistering disease caused by...
BACKGROUND: Patients with recessive dystrophic epidermolysis bullosa (RDEB) have deficiencies of col...
No effective or specific treatment is currently available for recessive dystrophic epidermolysis bul...
Recessive dystrophic epidermolysis bullosa (RDEB) is a severe skin fragility disorder caused by muta...
Genetic loss of collagen VII causes recessive dystrophic epidermolysis bullosa (RDEB)—a severe skin ...
University of Minnesota Ph.D. dissertation. 2021. Major: Molecular, Cellular, Developmental Biology ...
Context: Connective tissue cells include fibroblasts, chondrocytes, adipocyte, and osteocytes. These...
The heritable blistering disorder recessive dystrophic epidermolysis bullosa (RDEB) is a devastating...
BACKGROUND: Poorly healing wounds are one of the major complications in patients suffering from rece...
Mención Internacional en el título de doctorGenodermatoses are rare inherited skin diseases, mostly ...
2014-10-20Dystrophic epidermolysis bullosa (DEB) is a family of rare inherited mechano-bullous disor...
Inflammation is known to play a critical role in all stages of tumorigenesis; however, less is known...
Inflammation is known to play a critical role in all stages of tumorigenesis; however, less is known...
Background: Recessive dystrophic epidermolysis bullosa (RDEB) is an inherited blistering disease cau...
Inflammation is known to play a critical role in all stages of tumorigenesis; however, less is known...
Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a devastating skin blistering disease caused by...
BACKGROUND: Patients with recessive dystrophic epidermolysis bullosa (RDEB) have deficiencies of col...
No effective or specific treatment is currently available for recessive dystrophic epidermolysis bul...
Recessive dystrophic epidermolysis bullosa (RDEB) is a severe skin fragility disorder caused by muta...
Genetic loss of collagen VII causes recessive dystrophic epidermolysis bullosa (RDEB)—a severe skin ...
University of Minnesota Ph.D. dissertation. 2021. Major: Molecular, Cellular, Developmental Biology ...
Context: Connective tissue cells include fibroblasts, chondrocytes, adipocyte, and osteocytes. These...