Objective. Atherosclerosis is a chronic inflammatory disease which is responsible for many clinical manifestations. The present study was to investigate the anti-inflammatory functions and mechanisms of TNK1 in atherosclerosis. Methods. The ApoE(-/-) mice and human carotid endarterectomy (CEA) atherosclerotic plaques were used to investigate the differential expression of TNK1. The ApoE(-/-) mice were fed with high-fat diet (HFD) or normal-fat diet (NFD) for 8 weeks; the aorta was separated and stained with oil red O to evaluate the formation of atherosclerosis. TNK1 in mice aorta was measured by qPCR. The human CEA were obtained and identified as ruptured and stable plaques. The level of TNK1 was measured by qPCR and Western-blot staining....
Background: Atherosclerosis is an inflammatory process that develops in individuals with known risk ...
BACKGROUND: Previous studies implicated Toll-like receptor signaling as a critical pathogenic pathwa...
AbstractEndothelin-1 (ET-1) promotes atherosclerosis. We tested whether spleen tyrosine kinase (Syk)...
Background: Chronic activation of the innate immune system drives inflammation and contributes direc...
Objective: Atherosclerosis is an arterial occlusive disease with hypercholesterolemia and hypertensi...
Background: While the impact of inflammation as the substantial driving force of atherosclerosis has...
Background:\ua0Chronic activation of the innate immune system drives inflammation and contributes di...
Objective - Inflammation plays an important role in atherosclerosis. One of the most potent pro-infl...
Tumor necrosis factor-a in atherogenesis Stefan Jovinge, Department of Medicine, King Gustaf Vth Re...
Atherosclerosis (AS) is a chronic metabolic disease in arterial walls, characterized by lipid deposi...
TNF-α is present in atherosclerotic lesions, activates endothelial adhesion molecule expression, sti...
Background and aims: Atherosclerosis is critically fueled by vascular inflammation through oxidized ...
Background-Previous studies implicated Toll-like receptor signaling as a critical pathogenic pathway...
Background : Previous studies implicated Toll-like receptor signaling as a critical pathogenic pathw...
ObjectivesHerein, we determined the significance of tumor necrosis factor (TNF)-related apoptosis-in...
Background: Atherosclerosis is an inflammatory process that develops in individuals with known risk ...
BACKGROUND: Previous studies implicated Toll-like receptor signaling as a critical pathogenic pathwa...
AbstractEndothelin-1 (ET-1) promotes atherosclerosis. We tested whether spleen tyrosine kinase (Syk)...
Background: Chronic activation of the innate immune system drives inflammation and contributes direc...
Objective: Atherosclerosis is an arterial occlusive disease with hypercholesterolemia and hypertensi...
Background: While the impact of inflammation as the substantial driving force of atherosclerosis has...
Background:\ua0Chronic activation of the innate immune system drives inflammation and contributes di...
Objective - Inflammation plays an important role in atherosclerosis. One of the most potent pro-infl...
Tumor necrosis factor-a in atherogenesis Stefan Jovinge, Department of Medicine, King Gustaf Vth Re...
Atherosclerosis (AS) is a chronic metabolic disease in arterial walls, characterized by lipid deposi...
TNF-α is present in atherosclerotic lesions, activates endothelial adhesion molecule expression, sti...
Background and aims: Atherosclerosis is critically fueled by vascular inflammation through oxidized ...
Background-Previous studies implicated Toll-like receptor signaling as a critical pathogenic pathway...
Background : Previous studies implicated Toll-like receptor signaling as a critical pathogenic pathw...
ObjectivesHerein, we determined the significance of tumor necrosis factor (TNF)-related apoptosis-in...
Background: Atherosclerosis is an inflammatory process that develops in individuals with known risk ...
BACKGROUND: Previous studies implicated Toll-like receptor signaling as a critical pathogenic pathwa...
AbstractEndothelin-1 (ET-1) promotes atherosclerosis. We tested whether spleen tyrosine kinase (Syk)...