Serum-derived granulations and purported nanobacteria (NB) are pleomorphic apatite structures shown to resemble calcium granules widely distributed in nature. They appear to be assembled through a dual inhibitory-seeding mechanism involving proteinaceous factors, as determined by protease (trypsin and chymotrypsin) and heat inactivation studies. When inoculated into cell culture medium, the purified proteins fetuin-A and albumin fail to induce mineralization, but they will readily combine with exogenously added calcium and phosphate, even in submillimolar amounts, to form complexes that will undergo morphological transitions from nanoparticles to spindles, films, and aggregates. As a mineralization inhibitor, fetuin-A is much more potent th...
Genetic evidence from mutant mice suggests that α2-HS glycoprotein/fetuin-A (Ahsg) is a systemic inh...
International audience``Nanobacteria'', also known as nanons or calciprotein particles (CPP), are na...
The concentration of mineral solutes in mammalian blood is considerably higher than that predicted b...
Serum-derived granulations and purported nanobacteria (NB) are pleomorphic apatite structures shown ...
Calcium and apatite granulations are demonstrated here to form in both human and fetal bovine serum ...
Putative living entities called nanobacteria (NB) are unusual for their small sizes (50-500 nm), ple...
<p>Protein-mineral nanoparticles were prepared as described in <a href="http://www.plosone.org/artic...
<p>Protein-mineral nanoparticles were prepared as described in <a href="http://www.plosone.org/artic...
International audience"Nanobacteria" are nanometer-scale spherical and ovoid particles which have sp...
<p>(A) Fetuin-A and albumin in both metastable and supersaturated media: bovine serum fetuin-A (BSF)...
Mineralo-organic nanoparticles form spontaneously in human body fluids when the concentrations of ca...
Calcium phosphate stabilization by fetuin-A represents a model system for biomineralization research...
Genetic evidence from mutant mice suggests that α2-HS glycoprotein/fetuin-A (Ahsg) is a systemic inh...
International audience``Nanobacteria'', also known as nanons or calciprotein particles (CPP), are na...
The concentration of mineral solutes in mammalian blood is considerably higher than that predicted b...
Serum-derived granulations and purported nanobacteria (NB) are pleomorphic apatite structures shown ...
Calcium and apatite granulations are demonstrated here to form in both human and fetal bovine serum ...
Putative living entities called nanobacteria (NB) are unusual for their small sizes (50-500 nm), ple...
<p>Protein-mineral nanoparticles were prepared as described in <a href="http://www.plosone.org/artic...
<p>Protein-mineral nanoparticles were prepared as described in <a href="http://www.plosone.org/artic...
International audience"Nanobacteria" are nanometer-scale spherical and ovoid particles which have sp...
<p>(A) Fetuin-A and albumin in both metastable and supersaturated media: bovine serum fetuin-A (BSF)...
Mineralo-organic nanoparticles form spontaneously in human body fluids when the concentrations of ca...
Calcium phosphate stabilization by fetuin-A represents a model system for biomineralization research...
Genetic evidence from mutant mice suggests that α2-HS glycoprotein/fetuin-A (Ahsg) is a systemic inh...
International audience``Nanobacteria'', also known as nanons or calciprotein particles (CPP), are na...
The concentration of mineral solutes in mammalian blood is considerably higher than that predicted b...