The microtubule network is crucial for the developing nervous system and mutations in tubulin-encoding genes disrupt neuronal migration. In this issue, Tischfield et al. (2010) report that mutations in the neuronal TUBB3 gene have a striking impact on microtubule dynamics resulting in a diverse set of disease symptoms
The tubulin gene family is mainly expressed in post-mitotic neurons during cortical development with...
SummaryThe formation of the mammalian cortex requires the generation, migration, and differentiation...
One of the major challenges facing the long term survival of neurons is their requirement to maintai...
The microtubule network is crucial for the developing nervous system, and mutations in tubulin-encod...
Item does not contain fulltextMicrotubules are dynamic cytoskeletal elements coordinating and suppor...
SummaryWe report that eight heterozygous missense mutations in TUBB3, encoding the neuron-specific β...
We report that eight heterozygous missense mutations in TUBB3, encoding the neuron-specific beta-tub...
AbstractMutations in the microtubule cytoskeleton are linked to cognitive and locomotor defects duri...
The formation of the mammalian cortex requires the generation, migration, and differentiation of neu...
We report that eight heterozygous missense mutations in TUBB3, encoding the neuron-specific beta-tub...
Microtubules are dynamic cytoskeletal polymers that mediate numerous, essential functions such as ax...
© The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, pleas...
International audienceMalformations of Cortical Development (MCDs) are a group of severe brain malfo...
We report that eight heterozygous missense mutations in TUBB3, encoding the neuron-specific beta-tub...
Eight heterozygous missense muta- tions in TUBB3, encoding the neuron-specific b-tubulin isotype III...
The tubulin gene family is mainly expressed in post-mitotic neurons during cortical development with...
SummaryThe formation of the mammalian cortex requires the generation, migration, and differentiation...
One of the major challenges facing the long term survival of neurons is their requirement to maintai...
The microtubule network is crucial for the developing nervous system, and mutations in tubulin-encod...
Item does not contain fulltextMicrotubules are dynamic cytoskeletal elements coordinating and suppor...
SummaryWe report that eight heterozygous missense mutations in TUBB3, encoding the neuron-specific β...
We report that eight heterozygous missense mutations in TUBB3, encoding the neuron-specific beta-tub...
AbstractMutations in the microtubule cytoskeleton are linked to cognitive and locomotor defects duri...
The formation of the mammalian cortex requires the generation, migration, and differentiation of neu...
We report that eight heterozygous missense mutations in TUBB3, encoding the neuron-specific beta-tub...
Microtubules are dynamic cytoskeletal polymers that mediate numerous, essential functions such as ax...
© The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, pleas...
International audienceMalformations of Cortical Development (MCDs) are a group of severe brain malfo...
We report that eight heterozygous missense mutations in TUBB3, encoding the neuron-specific beta-tub...
Eight heterozygous missense muta- tions in TUBB3, encoding the neuron-specific b-tubulin isotype III...
The tubulin gene family is mainly expressed in post-mitotic neurons during cortical development with...
SummaryThe formation of the mammalian cortex requires the generation, migration, and differentiation...
One of the major challenges facing the long term survival of neurons is their requirement to maintai...