Background: Single nucleotide polymorphism (SNP) genotyping provides the means to develop a practical, rapid, inexpensive assay that will uniquely identify any Plasmodium falciparum parasite using a small amount of DNA. Such an assay could be used to distinguish recrudescence from re-infection in drug trials, to monitor the frequency and distribution of specific parasites in a patient population undergoing drug treatment or vaccine challenge, or for tracking samples and determining purity of isolates in the laboratory during culture adaptation and sub-cloning, as well as routine passage. Methods: A panel of twenty-four SNP markers has been identified that exhibit a high minor allele frequency (average MAF > 35%), for which robust Taq...
Malaria is a major public health problem that is actively being addressed in a global eradication ca...
Despite efforts to reduce malaria morbidity andmortality, drug-resistant parasites continue to evade...
Although Plasmodium vivax parasites are the predominant cause of malaria outside of sub-Saharan Afri...
Abstract Background Single nucleotide polymorphism (SNP) genotyping provides the means to develop a ...
Abstract Background Single nucleotide polymorphism (SNP) genotyping provides the means to develop a ...
International audiencePlasmodium vivax, one of the five species of Plasmodium parasites that cause h...
Plasmodium vivax, one of the five species of Plasmodium parasites that cause human malaria, is respo...
The diversity in the Plasmodium falciparum genome can be used to explore parasite population dynamic...
The diversity in the Plasmodium falciparum genome can be used to explore parasite population dynamic...
Plasmodium vivax, one of the five species of Plasmodium parasites that cause human ma-laria, is resp...
Background: Genomic surveillance of malaria parasite populations has the potential to inform control...
BACKGROUND: Genomic surveillance of malaria parasite populations has the potential to inform control...
Genetic diversity and population structure of Plasmodium falciparum are assessed here using three es...
AbstractMicroarray-based comparative genomic hybridizations (CGH) interrogate genomic DNA to identif...
Single nucleotide polymorphisms (SNPs) have been shown to be useful in revealing population structur...
Malaria is a major public health problem that is actively being addressed in a global eradication ca...
Despite efforts to reduce malaria morbidity andmortality, drug-resistant parasites continue to evade...
Although Plasmodium vivax parasites are the predominant cause of malaria outside of sub-Saharan Afri...
Abstract Background Single nucleotide polymorphism (SNP) genotyping provides the means to develop a ...
Abstract Background Single nucleotide polymorphism (SNP) genotyping provides the means to develop a ...
International audiencePlasmodium vivax, one of the five species of Plasmodium parasites that cause h...
Plasmodium vivax, one of the five species of Plasmodium parasites that cause human malaria, is respo...
The diversity in the Plasmodium falciparum genome can be used to explore parasite population dynamic...
The diversity in the Plasmodium falciparum genome can be used to explore parasite population dynamic...
Plasmodium vivax, one of the five species of Plasmodium parasites that cause human ma-laria, is resp...
Background: Genomic surveillance of malaria parasite populations has the potential to inform control...
BACKGROUND: Genomic surveillance of malaria parasite populations has the potential to inform control...
Genetic diversity and population structure of Plasmodium falciparum are assessed here using three es...
AbstractMicroarray-based comparative genomic hybridizations (CGH) interrogate genomic DNA to identif...
Single nucleotide polymorphisms (SNPs) have been shown to be useful in revealing population structur...
Malaria is a major public health problem that is actively being addressed in a global eradication ca...
Despite efforts to reduce malaria morbidity andmortality, drug-resistant parasites continue to evade...
Although Plasmodium vivax parasites are the predominant cause of malaria outside of sub-Saharan Afri...