LAMINA CRIBROSA IN GLAUCOMA: BIOMECHANICAL PROPERTIES AND POSSIBILITIES OF THEIR CLINICAL CONTROL

The literary review presents an analysis of modern views of the biomechanical properties of lamina cribrosa (LC) in glaucoma. It is shown that LC deformations in glaucomatous eyes are connected with their morphological and structural disorders at macro- and micro levels even in the early stages of glaucoma development. New visualization technologies of ocular structures, in particular, optical coherent tomography with enhanced depth imaging (EDI) enable in vivo evaluation of biomechanical characteristics of LC and its stress-strain from the data on the changing shape of its anterior surface (curvature index), thickness and deepness, pore dimensions, presence and severity of LC tissue defects. LC changes inherent to glaucoma are significant criteria for the estimation of the risk of glaucoma emergence and its early diagnostics, determination of the stage of the pathological process, and prediction of its progression rate. For citation: Kiseleva O.A., Iomdina E.N., Yakubova L.V., Khoziev D.D. Lamina cribrosa in glaucoma: biomechanical properties and possibilities of their clinical control. Russian ophthalmological journal. 2018; 11 (3):76-83 (In Russian). doi: 10.21516/2072-0076-2018-11-3-76-8