Overview of methods for determining polycyclic aromatic hydrocarbons in cigarette smoke, ETHS and ENDS aerosole, liquids for ENDS

The problem of improving the quality and reducing the toxicity of tobacco products is relevant and directly related to health. In 2008 the Russian Federation joined the WHO FCTC (Framework Convention of the World Health Organization on Tobacco Control) and since then has been pursuing a policy of applying and introducing WHO recommendations into the tobacco product regulatory system. In accordance with the current «Technical Regulations on Tobacco Products» of the Customs Union (ТР ТС 035/2014 TR), manufacturers are obliged to submit a report containing information on the composition of tobacco products sold during the reporting calendar year and on the substances they evolve in the form approved by the Eurasian Economic Commission (Article 6 of the TR CU 035/2014) annually to the authorized body of the Member State in the field of health. The information on the content of various toxic substances is provided in the report blank, which is now undergoing the procedure of consideration and approval. To assess and monitor the content of harmful toxic substances in cigarette smoke, in ETHS (electronic tobacco heating systems) and ENDS (electronic nicotine delivery systems) aerosols, the World Health Organization has determined the list of nine priority toxic components (benzapilene, formaldehyde, acetaldehyde, acrolein , nitrosonornicotine (NNN), 4-(N-methyl-N-nitrosamino-)-1-(3-pyridyl-)-1-butanone (NNK), benzene, 1,3-butadiene, carbon monoxide). The article deals with the chemical composition of tobacco smoke aerosol and the formation of polycyclic aromatic hydrocarbons (PAHs) in cigarette smoke. The chemical toxicological characteristics and review of methods for its determination are given. The necessity of developing a national standard for the determination of benzapilene to control the quality and safety of cigarettes, ENDS aerosol, ETHS, which are circulated on the Russian market, is substantiated