DETERMINATION OF THE CONTENTS OF NICOTINE, GLYCERIN AND PROPYLENE GLYCOL IN TOBACCO STICK FILLERS FOR ESHT

The need for constant monitoring of the content of substances in innovative nicotinecontaining products – heated tobacco – is due to possible risks to the health of consumers. The article describes the method for determining nicotine, glycerol and propylene glycol in stick fillers for electric tobacco heating systems (ESNT) using the gas chromatographic method, which includes the procedure for preparing the initial standard and extracting solutions, preparing calibration solutions, preparing a sample for analysis, chromatographic conditions. The results of the study to determine the content of nicotine, glycerol, propylene glycol in control samples of tobacco stick fillers for ESNT and a statistical analysis of the results have been presented. Experimental data on the content of nicotine, glycerol, propylene glycol in tobacco fillers in 15 commercial stick samples for electric systems of heated tobacco of Russian and foreign manufacturers have been presented. It has been experimentally confirmed that the component composition of tobacco stick fillers for ESNT depends on the formulation of the blendings and the characteristics of the manufacturing process. The developed procedure for the determination of nicotine, glycerol, and propylene glycol in the tobacco stick fillers for ESNT using the gas chromatographic method allows us to obtain reliable analysis results, to control the content of these substances in products, thereby identifying sources of possible danger to consumers in a timely manner