Introduction. In order to standardize the quality indicators during the expected shelf life of the developed drug naltrexone hydrochloride in the form of a nasal spray containing a high concentration of poloxamer and benzalkonium chloride as a preservative, a microbiological study was carried out. The possibility of using the membrane filtration method for testing prototypes recommended by the State Pharmacopoeia XIV.Aim. Study and selection of test conditions for the «microbiological purity» indicator of nasal spray samples containing naltrexone hydrochloride.Materials and methods. As an object of research, a naltrexone hydrochloride nasal spray was used. When analyzing the microbiological purity, the membrane filtration method recommended...
Introduction. An innovative antifungal agent based on hydrochloride with combination of PEG-400 and ...
Introduction: Naloxone is the antidote against heroin and other opioids. As a measure to combat over...
A screening method for determination of spill and leakage of 12 different antibiotic substances has ...
Introduction. Naltrexone, an antagonist of µ-opioid receptors, is promising for the treatment of var...
Introduction. Benzalkonium chloride is widely used as a conservation agent in medicines. For quantit...
The work is devoted to the development of nasal spray containing naltrexone hydrochloride. Naltrexon...
The aim of this work was the determination of microbiological purity of nasal ointment “Mnemastym” w...
Introduction. Acute toxicity of naltrexone hydrochloride nasal spray during intragastric administrat...
Objective. To explore the optimal concentration and antimicrobial effectiveness of antimicrobial pre...
Introduction. Naltrexone hydrochloride belongs to µ-opioid receptor antagonists and is widely used i...
Preservative efficacy tests were performed in triplicate on each of three batches of three formulate...
Preservative efficacy tests were performed in triplicate on each of three batches of three formulate...
Abstract Background Naltrexone has been proven to be an effective treatment option for the treatment...
Phenylephrine hydrochloride is a sympathomimetic with expressed local vasoconstrictor effect. Its ab...
Objective: The objective of the present research work was to develop and validate reversed-phase hig...
Introduction. An innovative antifungal agent based on hydrochloride with combination of PEG-400 and ...
Introduction: Naloxone is the antidote against heroin and other opioids. As a measure to combat over...
A screening method for determination of spill and leakage of 12 different antibiotic substances has ...
Introduction. Naltrexone, an antagonist of µ-opioid receptors, is promising for the treatment of var...
Introduction. Benzalkonium chloride is widely used as a conservation agent in medicines. For quantit...
The work is devoted to the development of nasal spray containing naltrexone hydrochloride. Naltrexon...
The aim of this work was the determination of microbiological purity of nasal ointment “Mnemastym” w...
Introduction. Acute toxicity of naltrexone hydrochloride nasal spray during intragastric administrat...
Objective. To explore the optimal concentration and antimicrobial effectiveness of antimicrobial pre...
Introduction. Naltrexone hydrochloride belongs to µ-opioid receptor antagonists and is widely used i...
Preservative efficacy tests were performed in triplicate on each of three batches of three formulate...
Preservative efficacy tests were performed in triplicate on each of three batches of three formulate...
Abstract Background Naltrexone has been proven to be an effective treatment option for the treatment...
Phenylephrine hydrochloride is a sympathomimetic with expressed local vasoconstrictor effect. Its ab...
Objective: The objective of the present research work was to develop and validate reversed-phase hig...
Introduction. An innovative antifungal agent based on hydrochloride with combination of PEG-400 and ...
Introduction: Naloxone is the antidote against heroin and other opioids. As a measure to combat over...
A screening method for determination of spill and leakage of 12 different antibiotic substances has ...