ACE inhibitor fosinopril in the treatment of hypertension: potential benefits

Fosinopril with dual clearance can be used in renal failure without dose correction, which may be required in diabetes or elderly patients even with normal creatinine level in blood plasma. Therefore, fosinopril can be indicated as the drug of choice in patients with renal failure and high risk of kidney disease. Fosinopril can be used either as monotherapy or in combination with hydrochlorothiazide, including fixed combinations