Premenstrual syndrome: the effectiveness of treatment with a drospirenone-containing contraceptive

Premenstrual syndrome (PMS) is a frequent disorder associated with the menstrual cycle; treatments include a variety of medicinal and non-medicinal methods, primarily due to the absence of a common theory for the development of PMS. The majority of authors see premenstrual syndrome as a heterogeneous condition. Combined hormonal contraception is a pathogenetically substantiated method of PMS treatment. The study involved 122 patients with moderate to severe PMS. The diagnosis was confirmed by a prospective assessment of diaries. Participants received a drug containing 3 mg drospirenone and 20 µg ethinyl estradiol within 24/4 regimen. A pronounced positive effect of COC treatment was largely achieved in respect of psychological symptoms of PMS