IRRITABLE BOWEL SYNDROME AND ITS RELATIONSHIP WITH INTESTINAL MICROFLORA

In the last decade there has been a very active study of large microbial community in the human gut. The concept appeared explaining the development and persistence of symptoms in irritable bowel syndrome due to disturbances of the intestinal microbial landscape. Manipulation of the intestinal microflora represents a new strategy for treatment of this polietiologic disease. The modulation of the intestinal bacterial at which beneficial (Lactobacilli and Bifidobacteria) bacteria are increased and pathogenic bacteria (Clostridium, Escherichia coli, Salmonella, Shigella and Pseudomonas) are reduced should reduce the symptoms of the irritable bowel syndrome. In this conceptual framework, probiotics are the optimal option in terms of efficacy and safety, and they attract the attention of specialists prebiotics, synbiotics, antibiotics and fecal transplantation