The article provides data on 114 patients with stage 2 primary arterial hypertension (AH) according to the WHO classification (2008) and the development of complications associated with hemostasis violations depending on the nationality of patients (Mordva-Moksha, Russians) and polymorphism methyltetrahydrofolate reductase (MTHFR) gene carrier state. Polymorphic genotypes were identified using polymerase chain reaction (PCR) along with traditional clinical and instrumental studies. The analysis of MTHFR gene polymorphic genotypes carriage showed a significant predominance of intermediate genotypes (88% – CT genotype at position 677, 66% – AC genotype at position 1298) regardless of nationality of patients with AH. The carriage of “unfavoura...
Background: Coronary artery disease (CAD) is the most prevalent form of cardiovascular disease that ...
International audienceEssential hypertension (EH) is a common, multifactorial disorder likely to be ...
Methylenetetrahydrofolate reductase (MTHFR) is involved in the reduction of 5,10-methylenetetrahydro...
OBJECTIVE: The research is devoted to the studying of the C677T polymorphism of the MTHFR gene among...
Objectives. To check for the association of genetic polymorphisms related to the methylenetetrahydro...
The current study was conducted to determine whether there is a relation between hypertension and tw...
Association of polymorphic markers rs243865 and rs3025058 with the development of arterial hypertens...
Background: Hypertension is a multifactorial disease caused by the interaction between genetic and e...
Objective. Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme of homocysteine metabolism an...
BACKGROUND AND OBJECTIVE: Hyperhomocysteinemia, due to a combination of genetic and environmental fa...
The aim of this study was to investigate the association between functional polymorphism C677T (rs18...
Three clinically important mutations; Two of the methyltetrahydrofolatereductase (MTHFR) gene namely...
The methylenetetrahydrofolate reductase (MTHFR) gene has been associated with increased risk for car...
CONTEXT AND OBJECTIVE: Obstructive coronary artery disease (CAD) is characterized by the deposition ...
Vascular disease is a serious public health problem in the industrialized world, and is a frequent c...
Background: Coronary artery disease (CAD) is the most prevalent form of cardiovascular disease that ...
International audienceEssential hypertension (EH) is a common, multifactorial disorder likely to be ...
Methylenetetrahydrofolate reductase (MTHFR) is involved in the reduction of 5,10-methylenetetrahydro...
OBJECTIVE: The research is devoted to the studying of the C677T polymorphism of the MTHFR gene among...
Objectives. To check for the association of genetic polymorphisms related to the methylenetetrahydro...
The current study was conducted to determine whether there is a relation between hypertension and tw...
Association of polymorphic markers rs243865 and rs3025058 with the development of arterial hypertens...
Background: Hypertension is a multifactorial disease caused by the interaction between genetic and e...
Objective. Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme of homocysteine metabolism an...
BACKGROUND AND OBJECTIVE: Hyperhomocysteinemia, due to a combination of genetic and environmental fa...
The aim of this study was to investigate the association between functional polymorphism C677T (rs18...
Three clinically important mutations; Two of the methyltetrahydrofolatereductase (MTHFR) gene namely...
The methylenetetrahydrofolate reductase (MTHFR) gene has been associated with increased risk for car...
CONTEXT AND OBJECTIVE: Obstructive coronary artery disease (CAD) is characterized by the deposition ...
Vascular disease is a serious public health problem in the industrialized world, and is a frequent c...
Background: Coronary artery disease (CAD) is the most prevalent form of cardiovascular disease that ...
International audienceEssential hypertension (EH) is a common, multifactorial disorder likely to be ...
Methylenetetrahydrofolate reductase (MTHFR) is involved in the reduction of 5,10-methylenetetrahydro...