Possibilities of topical antibacterial drugs in practice of ENT-doctors

Introduction. Antibiotic resistance is a topic that is currently causing concern for all of humanity in the world. Experts at the World Health Organization consider it a global threat. Irrational and uncontrolled use of antibacterial drugs, the low level of prevention of bacterial and viral infections have led to an increase in mutations and the emergence of new resistant strains of microorganisms. The growth of antimicrobial resistance dictates the search for alternatives to systemic antibiotic therapy. In this connection, the search for an alternative to systemic antibiotic therapy is relevant.Goal of research. This article discusses the use of a topical antibacterial drug tiamphenicol glycinate acetylcysteinate, which is a combination of a broad-spectrum antibiotic and a mucolytic.Materials and methods. A literature review was conducted with an analysis of scientific research data on the effectiveness of the topical antibacterial drug tiamphenicol glycinate acetylcysteinate.Results. In the practice of an otorhinolaryngologist topical use of tiamphenicol glycinate acetylcysteinate, including inhalation, helps to improve the course and prognosis of the disease, reduce the recovery time, and in some cases, reduce the systemic antibiotic use.Conclusion. The obtained data allow us to recommend topical antibacterial drug tiamphenicol glycinate acetylcysteinate for use in otorhinolaryngological practice