A recent increase in the number of safety signals of varying quality being submitted to the national and industry databases calls for the development of formalized search and analysis algorithms. The aim of the study was to develop an approach to identification and evaluation of safety signals in the database of an expert institution containing notifications of serious adverse events (SAE) that occurred during clinical trials. A specific feature of this approach is that it can be used in limited databases which, unlike international databases containing millions of reports (VigiBase, EudraVigilance), preclude the use of statistical methods for measurement of disproportionality. The proposed approach consists in evaluation of several criteri...
In 1968 the World Health Organisation initiated the development of an international programme for co...
Purpose Data mining on electronic health records (EHRs) has emerged as a promising complementary met...
In the last 5 years, regulatory agencies and drug monitoring centres have beenAbstract developing co...
Background The growing interest in using electronic healthcare record (EHR) databases for drug safet...
Background: The growing interest in using electronic healthcare record (EHR) databases for drug safe...
BACKGROUND: Drug safety monitoring relies primarily on spontaneous reporting, but electronic health ...
BACKGROUND: Drug safety monitoring relies primarily on spontaneous reporting, but electronic health ...
Background: Drug safety monitoring relies primarily on spontaneous reporting, but electronic health ...
INTRODUCTION: Signal detection from healthcare databases is possible, but is not yet used for routin...
A prospective pharmacovigilance signal detection study, comparing the real-world healthcare data (EU...
BACKGROUND: Drug safety monitoring relies primarily on spontaneous reporting, but electronic heal...
A principle concern of pharmacovigilance is the timely detection of adverse drug reactions that are ...
PURPOSE: Signal detection is a crucial step in the discovery of post-marketing adverse drug reaction...
Robust tools for monitoring the safety of marketed therapeutic products are of paramount importance ...
Adverse drug reactions (ADRs) represent an important risk for patients and have a significant econom...
In 1968 the World Health Organisation initiated the development of an international programme for co...
Purpose Data mining on electronic health records (EHRs) has emerged as a promising complementary met...
In the last 5 years, regulatory agencies and drug monitoring centres have beenAbstract developing co...
Background The growing interest in using electronic healthcare record (EHR) databases for drug safet...
Background: The growing interest in using electronic healthcare record (EHR) databases for drug safe...
BACKGROUND: Drug safety monitoring relies primarily on spontaneous reporting, but electronic health ...
BACKGROUND: Drug safety monitoring relies primarily on spontaneous reporting, but electronic health ...
Background: Drug safety monitoring relies primarily on spontaneous reporting, but electronic health ...
INTRODUCTION: Signal detection from healthcare databases is possible, but is not yet used for routin...
A prospective pharmacovigilance signal detection study, comparing the real-world healthcare data (EU...
BACKGROUND: Drug safety monitoring relies primarily on spontaneous reporting, but electronic heal...
A principle concern of pharmacovigilance is the timely detection of adverse drug reactions that are ...
PURPOSE: Signal detection is a crucial step in the discovery of post-marketing adverse drug reaction...
Robust tools for monitoring the safety of marketed therapeutic products are of paramount importance ...
Adverse drug reactions (ADRs) represent an important risk for patients and have a significant econom...
In 1968 the World Health Organisation initiated the development of an international programme for co...
Purpose Data mining on electronic health records (EHRs) has emerged as a promising complementary met...
In the last 5 years, regulatory agencies and drug monitoring centres have beenAbstract developing co...