Polycomb Group complexes maintain gene repression through the incorporation of H2AK121ub and H3K27me3. Here, the authors show that H2AK121ub marks less accessible but transcriptionally permissive chromatin, while H3K27me3 enforces a repressed transcriptionally less-permissive state
Abstract Background Although spatial organization of compartments and topologically associating doma...
Constitutive heterochromatin is associated with repressive epigenetic modifications of histones and ...
Background Histone variants establish structural and functional diversity of chromatin by affecting...
Although it is well established that the Polycomb Group (PcG) complexes maintain gene repression thr...
International audienceIn animals, distant H3K27me3-marked Polycomb targets can establish physical in...
The histone modification H3K27me3 is involved in repression of transcription and plays a crucial rol...
H3K27me3 is a transcriptional repressive epigenetic mark that plays vital roles in many biological p...
Background: Polycomb group complexes PRC1 and PRC2 repress gene expression at the chromatin level in...
[Background]: Stable gene repression is essential for normal growth and development. Polycomb repres...
Summary: While the pivotal role of linker histone H1 in shaping nucleosome organization is well esta...
Polycomb group (PcG) proteins are essential to maintain gene expression patterns during development....
Precise spatio-temporal regulation of gene expression is required for development of multicellular o...
The histone modification H3K27me3 is involved in repression of transcription and plays a crucial rol...
Trimethylation of histone H3 lysine 27 (H3K27me3) plays critical roles in regulating animal developm...
International audienceTranscriptional activity and structure of chromatin are correlated with patter...
Abstract Background Although spatial organization of compartments and topologically associating doma...
Constitutive heterochromatin is associated with repressive epigenetic modifications of histones and ...
Background Histone variants establish structural and functional diversity of chromatin by affecting...
Although it is well established that the Polycomb Group (PcG) complexes maintain gene repression thr...
International audienceIn animals, distant H3K27me3-marked Polycomb targets can establish physical in...
The histone modification H3K27me3 is involved in repression of transcription and plays a crucial rol...
H3K27me3 is a transcriptional repressive epigenetic mark that plays vital roles in many biological p...
Background: Polycomb group complexes PRC1 and PRC2 repress gene expression at the chromatin level in...
[Background]: Stable gene repression is essential for normal growth and development. Polycomb repres...
Summary: While the pivotal role of linker histone H1 in shaping nucleosome organization is well esta...
Polycomb group (PcG) proteins are essential to maintain gene expression patterns during development....
Precise spatio-temporal regulation of gene expression is required for development of multicellular o...
The histone modification H3K27me3 is involved in repression of transcription and plays a crucial rol...
Trimethylation of histone H3 lysine 27 (H3K27me3) plays critical roles in regulating animal developm...
International audienceTranscriptional activity and structure of chromatin are correlated with patter...
Abstract Background Although spatial organization of compartments and topologically associating doma...
Constitutive heterochromatin is associated with repressive epigenetic modifications of histones and ...
Background Histone variants establish structural and functional diversity of chromatin by affecting...