Biochemical evaluation between obese carriers and non-carriers of polycystic ovary syndrome

Objective: To perform a biochemical analysis of the lipid and glycemic profiles comparative between obese patients with and without Polycystic Ovary Syndrome (PCOS). Method: Cross-sectional case-control study through biochemical laboratory tests for lipid and glycemic profile in two groups of volunteers, obese carriers and non-carriers of PCOS. Statistical analyzes were performed using nonparametric (Mann-Whitney) and parametric (t-student) tests using statistically significant values for p <0.05. Results: The analysis of biochemical parameters showed statistically and biologically significant differences between the analyzed items. Changes in lipid profile were clinically relevant between the groups, with carriers with high LDL clinical risk levels. Both carriers and non-carriers showed no changes in fasting glucose, with levels within the reference. However, HbA1c showed clinical difference between the groups, but not statistically significant, emphasizing that 50% of the patients with PCOS are at increased risk for developing DM. Conclusion: It was possible to verify that obese patients with PCOS are more prone to the risks of diabetes and cardiovascular diseases compared to non-carriers.