Run Out Tables (ROTs) have been used for long time in order to achieve different microstructure of steel in the industries. The microstructure of steel controlled by the cooling rate which in turn depends on various factors like the plate velocity, nozzle bank distance, coolant flow rate, and many others. Achieving new steel grade thus demand a proper combination setting of all such parameters. The observed data like upper nozzle distance, lower nozzle distance and mass flow rate of coolant from the laboratory scale ROTs are used to find out the cooling rate which is important parameter for achieving desired properties in steel. An Artificial Neural Network has been used here to creating an empirical relation between the observed data and t...