Epidemiological studies revealed that antibiotics exposure increases a risk of inflammatory bowel diseases (IBD) development. It remained largely unknown how antibiotic-induced dysbiosis confers the risk for enhanced inflammatory response. The aim of the present study was to test the hypothesis that SCFAs, their receptors and transporters mediate the antibiotic long-term effects on the functional state of colonic mucosa and susceptibility to the experimental colitis. Male Wistar rats were treated daily for 14 days with antibiotic ceftriaxone (300 mg/kg, i.m.) or vehicle; euthanized by CO2 inhalation followed by cervical dislocation in 1, 14 or 56 days after antibiotic withdrawal. We found increased cecum weight and sustained changes in micr...
Non-digestible oligosaccharides (NDO) were shown to reduce inflammation in experimental colitis, but...
Mucosal surface of the gut is in continuous contact with foreign compounds derived from diet as well...
BACKGROUND:Some probiotic strains have the potential to assist in relieving the symptoms of inflamma...
Short-chain fatty acids (SCFAs) are major products of the microbial fermentation of dietary fiber in...
Antibiotic treatment increases susceptibility to development of inflammatory bowel diseases (IBD) bo...
Microflora plays a critical role in the initiation and development of inflammatory bowel disease (IB...
The present study was carried out to test the colonic mucosal response of rats to oral supplementati...
Disturbed homeostasis of gut microbiota has been suggested to be closely associated with 5-fluoroura...
Inflammatory Bowel diseases (IBDs) constitute a complex panel of disorders characterized with chroni...
Macrophages in the healthy intestine are highly specialized and usually respond to the gut microbiot...
International audienceObjective: Data from clinical research suggest that certain probiotic bacteria...
Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as Inflammatory Bowel Diseases ...
OBJECTIVE: Data from clinical research suggest that certain probiotic bacterial strains have the pot...
As we learn more about the importance of our microbiome in inflammatory, metabolic, and functional d...
Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as Inflammatory Bowel Diseases ...
Non-digestible oligosaccharides (NDO) were shown to reduce inflammation in experimental colitis, but...
Mucosal surface of the gut is in continuous contact with foreign compounds derived from diet as well...
BACKGROUND:Some probiotic strains have the potential to assist in relieving the symptoms of inflamma...
Short-chain fatty acids (SCFAs) are major products of the microbial fermentation of dietary fiber in...
Antibiotic treatment increases susceptibility to development of inflammatory bowel diseases (IBD) bo...
Microflora plays a critical role in the initiation and development of inflammatory bowel disease (IB...
The present study was carried out to test the colonic mucosal response of rats to oral supplementati...
Disturbed homeostasis of gut microbiota has been suggested to be closely associated with 5-fluoroura...
Inflammatory Bowel diseases (IBDs) constitute a complex panel of disorders characterized with chroni...
Macrophages in the healthy intestine are highly specialized and usually respond to the gut microbiot...
International audienceObjective: Data from clinical research suggest that certain probiotic bacteria...
Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as Inflammatory Bowel Diseases ...
OBJECTIVE: Data from clinical research suggest that certain probiotic bacterial strains have the pot...
As we learn more about the importance of our microbiome in inflammatory, metabolic, and functional d...
Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as Inflammatory Bowel Diseases ...
Non-digestible oligosaccharides (NDO) were shown to reduce inflammation in experimental colitis, but...
Mucosal surface of the gut is in continuous contact with foreign compounds derived from diet as well...
BACKGROUND:Some probiotic strains have the potential to assist in relieving the symptoms of inflamma...