BackgroundThe imbalance between pro- and anti-inflammatory immune responses plays a pivotal role in chronic obstructive pulmonary disease (COPD) development and progression. To clarify the pathophysiological mechanisms of this disease, we performed a temporal analysis of immune response-mediated inflammatory progression in a cigarette smoke (CS)-induced mouse model with a focus on the balance between Th17 and Treg responses.MethodsC57BL/6 mice were exposed to CS for 1, 3 or 6 months to induce COPD, and the control groups were maintained under filtered air conditions for the same time intervals. We then performed functional (respiratory mechanics) and structural (alveolar enlargement) analyses. We also quantified the NF-κB, TNF-α, CD4, CD8, ...
Background: Chronic obstructive pulmonary disease (COPD) is characterized by progressive loss of lun...
Chronic obstructive pulmonary disease (COPD) is characterized by chronic pulmonary and systematic in...
AbstractProgression of chronic obstructive pulmonary disease (COPD) is linked to episodes of exacerb...
INTRODUÇÃO: O desequilíbrio entre as respostas imunes pró- e anti-inflamatórias, mediado pela via T ...
Neutrophilic inflammation results in loss of lung function in chronic obstructive pulmonary disease ...
Chronic obstructive pulmonary disease (COPD) is associated with irreversible persistent airflow limi...
COPD (chronic obstructive pulmonary disease) is caused by exposure to toxic gases and particles, mos...
Objectives: Innate lymphoid cells (ILCs) secrete cytokines, such as IFN-γ, IL-13 and IL-17, which ar...
SummaryBackgroundChronic obstructive pulmonary disease (COPD) is a progressive disorder characterize...
International audienceChronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease...
Cigarette smoke (CS) is the major cause of chronic obstructive pulmonary disease (COPD). Interleukin...
Chronic obstructive pulmonary disease (COPD) is characterized by chronic pulmonary and systematic in...
Introduction — Currently, chronic obstructive pulmonary disease (COPD) is a global public health pro...
Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome associated with abnormal in...
COPD (chronic obstructive pulmonary disease) is a major incurable global health burden and will beco...
Background: Chronic obstructive pulmonary disease (COPD) is characterized by progressive loss of lun...
Chronic obstructive pulmonary disease (COPD) is characterized by chronic pulmonary and systematic in...
AbstractProgression of chronic obstructive pulmonary disease (COPD) is linked to episodes of exacerb...
INTRODUÇÃO: O desequilíbrio entre as respostas imunes pró- e anti-inflamatórias, mediado pela via T ...
Neutrophilic inflammation results in loss of lung function in chronic obstructive pulmonary disease ...
Chronic obstructive pulmonary disease (COPD) is associated with irreversible persistent airflow limi...
COPD (chronic obstructive pulmonary disease) is caused by exposure to toxic gases and particles, mos...
Objectives: Innate lymphoid cells (ILCs) secrete cytokines, such as IFN-γ, IL-13 and IL-17, which ar...
SummaryBackgroundChronic obstructive pulmonary disease (COPD) is a progressive disorder characterize...
International audienceChronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease...
Cigarette smoke (CS) is the major cause of chronic obstructive pulmonary disease (COPD). Interleukin...
Chronic obstructive pulmonary disease (COPD) is characterized by chronic pulmonary and systematic in...
Introduction — Currently, chronic obstructive pulmonary disease (COPD) is a global public health pro...
Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome associated with abnormal in...
COPD (chronic obstructive pulmonary disease) is a major incurable global health burden and will beco...
Background: Chronic obstructive pulmonary disease (COPD) is characterized by progressive loss of lun...
Chronic obstructive pulmonary disease (COPD) is characterized by chronic pulmonary and systematic in...
AbstractProgression of chronic obstructive pulmonary disease (COPD) is linked to episodes of exacerb...