A Study of the correlation between radiological and histopathological findings in intracranial lesions

Objective: This study was conducted to formulate locationwise radiologic diagnostic algorithms and assess their concordance with the final histopathological diagnosis of intracranial mass lesions to evaluate their utility in a rural setting where only basic facilities are available. Material and Method: In present study seventy two cases were analyzed.Histopathological evaluation was done from biopsy sample sent in formalin, tissue processing was done by standard procedure, tissue sections were routinely stained by H&E, immunohistochemical examination was performed in case of histopathological discrepancies. Radiological findings were correlated with histopathological diagnosis and concordances were calculated. Statistical Analysis: Frequencies and crosstabs were used for calculation. Result: This was a study of seventy-two patients with age ranging from 9months to 65 years. In these entire 72 cases, male patients were 42(58%), female patients were 30(42%). M: F was 1.38:1. Most of patient presented with headache, and frontal lobe was the most common location. In all these lesions, 88.8% cases were neoplastic lesions. Among all neoplastic lesions, 52.7% were malignant tumors and 34.7% were benign tumors. Among all malignant tumors, Astrocytoma was the most common malignant tumor.Meningioma was the second most commonly encountered lesion. In the present study radiological and histopathological correlation was present in84.7% of cases. IHC was performed wherever needed, to support diagnosis. Conclusion: Radiological investigations are reliable diagnostic tools for space occupying central nervous system lesions, but histopathology is still the gold standard. So multidisciplinary approach is the ideal approach for space occupying lesions of central nervous syste