Correlation between Occupational Stress and Coronary Heart Disease in Northwestern China: A Case Study of Xinjiang

Objective. To study the correlation between occupational stress and coronary heart disease in western China. Method. A case-control design was used. From June 2016 to May 2017, 310 patients with coronary heart disease (CHD) confirmed by coronary angiography (CAG) at the Heart Center of the First Affiliated Hospital of Xinjiang Medical University were recruited by cluster sampling, along with 536 healthy controls. The questionnaire was developed based on a Job Content Questionnaire (JCQ). An epidemiological survey was conducted to collect clinical data. Chi-squared test, analysis of variance, and binary logistic regression analysis were adopted. Results. (1) In the Han population, there were statistically significant differences in the composition of smoking, diets, sleep duration, sleep quality, and physical activity between two groups (all P0.05). In the Han and Uygur case groups, the difference between the occupational stress level and Gensini high-level group were statistically significant (P<0.05). (6) After adjustment for age and sex, significant increased risk effects for Han patients with CHD were found to be associated with sleep quality (OR=1.88; 95% CI: 1.047-1.782; P<0.05). Uygur patients with CHD was significantly associated with smoking (OR=3.094; 95% CI: 1.025-1.103; P<0.05) and occupation stress (OR=1.523; 95% CI: 1.757-3.062; P