Generation, localization and functions of macrophages during the development of testis

Emmi Lokka
Laura Lintukorpi
Sheyla Cisneros-Montalvo
Juho-Antti Mäkelä
Sofia Tyystjärvi
Venla Ojasalo
Heidi Gerke
Jorma Toppari
Pia Rantakari
Marko Salmi

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Publication date

September 2020

DOI

10.1038/s41467-020-18206-0

Publisher

Springer Science and Business Media LLC

Journal

Nature Communications

Abstract

The developmental origins and functions of testis macrophages remain incompletely characterized. Here, the authors show, using histology, high-dimensional mass cytometry and cell fate-mapping data, that interstitial and peritubular macrophages originate from distinct precursors and contribute distinctly to spermatogenesis

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Generation, localization and functions of macrophages during the development of testis

Abstract

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Generation, localization and functions of macrophages during the development of testis

Abstract

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