Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd

Christiane Brugger
Cheng Zhang
Margaret M. Suhanovsky
David D. Kim
Amy N. Sinclair
Dmitry Lyumkis
Alexandra M. Deaconescu

Open link

Publication date

July 2020

DOI

10.1038/s41467-020-17457-1

Publisher

Springer Science and Business Media LLC

Journal

Nature Communications

Abstract

Transcription-repair coupling factors (TRCFs) are large ATPases that mediate the preferential repair of the transcribed DNA strand. Here the authors reveal the cryo-EM structure of DNA-bound Mfd, the bacterial TRCF, and provide molecular insights into its mode of action

Extracted data

We use cookies to provide a better user experience.

Data Protection

Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd

Abstract

Extracted data

Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd

Abstract

Extracted data

Topics

Related items

Topics

Related items