Humans carry residues of multiple synthetic chemicals at any given point in time. Research has demonstrated that compounds with varying molecular initiating events (MIE) that disrupt common key events can act in concert to produce cumulative adverse effects. Congenital defects of the male reproductive tract are some of the most frequently diagnosed malformations in humans and chemical exposures in utero can produce these effects in laboratory animals and humans. Here, we hypothesized that in utero exposure to a mixture of pesticides and phthalates, each of which produce male reproductive tract defects individually, would produce cumulative effects even when each chemical is present at a no observed adverse effect level (NOAEL) specific for ...
We investigated the effects of maternal exposure to the plasticizer di(2-ethylhexyl) phthalate (DEHP...
This study was designed to develop and validate a short-term in vivo protocol termed the Fetal Phtha...
With the limited but ongoing usage of di-n-butyl phthalate (DBP) as plasticizer, the health effects ...
Exposure to plasticizers di(n-butyl) phthalate (DBP) and diethylhexyl phthalate (DEHP) during sexual...
Reproductive malformations such as hypospadias, cryptorchidism and testicular cancer appear to be on...
Humans are inevitably exposed to ubiquitous phthalate esters (PAEs). In utero exposure to di-n-butyl...
Mayer–Rokitansky–Kuster–Hauser (MRKH) syndrome is characterized by uterine and vaginal canal aplasia...
Phthalate diesters are chemicals to which humans are ubiquitously exposed. Exposure to certain phtha...
By diminishing the action of androgens during gestation, certain chemicals can induce irreversible d...
Testis function in fetal and peripubertal male rats is disrupted by subchronic exposure to phthalate...
Di-2-ethylhexyl phthalate (DEHP) and other phthalate esters are potent peroxisome proliferator plast...
Prochloraz is a commonly used fungicide that has shown multiple mechanisms of action in vitro. It an...
Diethylhexyl phthalate (DEHP) is present in medical devices, packaging and food containers, from whe...
There are great concerns about the increasing incidence of abnormalities in male reproductive functi...
This study was designed to develop and validate a short-term in vivo protocol termed the Fetal Phtha...
We investigated the effects of maternal exposure to the plasticizer di(2-ethylhexyl) phthalate (DEHP...
This study was designed to develop and validate a short-term in vivo protocol termed the Fetal Phtha...
With the limited but ongoing usage of di-n-butyl phthalate (DBP) as plasticizer, the health effects ...
Exposure to plasticizers di(n-butyl) phthalate (DBP) and diethylhexyl phthalate (DEHP) during sexual...
Reproductive malformations such as hypospadias, cryptorchidism and testicular cancer appear to be on...
Humans are inevitably exposed to ubiquitous phthalate esters (PAEs). In utero exposure to di-n-butyl...
Mayer–Rokitansky–Kuster–Hauser (MRKH) syndrome is characterized by uterine and vaginal canal aplasia...
Phthalate diesters are chemicals to which humans are ubiquitously exposed. Exposure to certain phtha...
By diminishing the action of androgens during gestation, certain chemicals can induce irreversible d...
Testis function in fetal and peripubertal male rats is disrupted by subchronic exposure to phthalate...
Di-2-ethylhexyl phthalate (DEHP) and other phthalate esters are potent peroxisome proliferator plast...
Prochloraz is a commonly used fungicide that has shown multiple mechanisms of action in vitro. It an...
Diethylhexyl phthalate (DEHP) is present in medical devices, packaging and food containers, from whe...
There are great concerns about the increasing incidence of abnormalities in male reproductive functi...
This study was designed to develop and validate a short-term in vivo protocol termed the Fetal Phtha...
We investigated the effects of maternal exposure to the plasticizer di(2-ethylhexyl) phthalate (DEHP...
This study was designed to develop and validate a short-term in vivo protocol termed the Fetal Phtha...
With the limited but ongoing usage of di-n-butyl phthalate (DBP) as plasticizer, the health effects ...