Transplantation of discarded livers following viability testing with normothermic machine perfusion
- Hynek Mergental
- Richard W. Laing
- Amanda J. Kirkham
- M. Thamara P. R. Perera
- Yuri L. Boteon
- Joseph Attard
- Darren Barton
- Stuart Curbishley
- Manpreet Wilkhu
- Desley A. H. Neil
- Stefan G. Hübscher
- Paolo Muiesan
- John R. Isaac
- Keith J. Roberts
- Manuel Abradelo
- Andrea Schlegel
- James Ferguson
- Hentie Cilliers
- Julian Bion
- David H. Adams
- Chris Morris
- Peter J. Friend
- Christina Yap
- Simon C. Afford
- Darius F. Mirza
Publication date
June 2020
DOI Publisher
Springer Science and Business Media LLC Journal
Nature CommunicationsAbstract
The shortage of viable donated livers limits patient access to liver transplantation. Here the authors report the use of normothermic machine perfusion to help identify viable organs from livers discarded based on current clinical criteria, which are then transplanted to recipients in a single-arm clinical trial
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