Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1994.Vita.Includes bibliographical references.by Sandra Ann Filla.Ph.D
New (+)-discodermolide analogs were designed by Professor Mark A. Lipton using FEP calculations to s...
Thesis advisor: James P. Morken(+)-Discodermolide is a marine natural product and is one of the most...
[structure: see text] Two hybrid analogues of discodermolide and dictyostatin (3, 26) have been desi...
The dissertation contained herein describes studies concerning the natural product (+)-discodermolid...
The marine sponge-derived polyketide discodermolide is a potent antimitotic agent that represents a ...
A highly convergent and stereocontrolled total synthesis of ($-$)-discodermolide (1), antipode of po...
An approach to the asymmetric synthesis of fragments corresponding to C1---C7 and C15---C24 of (+)-d...
Coupling Of C9-14 (4) and C15-21 (5a) fragments to produce the cis-trisubstituted olefin was achieve...
The dissertation contained herein describes synthetic studies of (+)-discodermolide (1), a deep-sea ...
In 1990, the natural product discodermolide was isolated from a marine sponge and later found to hav...
The application of the [2,3] Wittig rearrangement to the total synthesis of (+)-discodermolide is th...
International audienceThis account describes an efficient and modulable total synthesis of (+)-disco...
Discodermolide was discovered in 1990 and with its discovery set off an expansive\ud medicinal chemi...
[structure: see text] Four truncated analogues of the natural product discodermolide were synthesize...
A novel total synthesis of the complex polyketide (+)-discodermolide, a promising anticancer agent o...
New (+)-discodermolide analogs were designed by Professor Mark A. Lipton using FEP calculations to s...
Thesis advisor: James P. Morken(+)-Discodermolide is a marine natural product and is one of the most...
[structure: see text] Two hybrid analogues of discodermolide and dictyostatin (3, 26) have been desi...
The dissertation contained herein describes studies concerning the natural product (+)-discodermolid...
The marine sponge-derived polyketide discodermolide is a potent antimitotic agent that represents a ...
A highly convergent and stereocontrolled total synthesis of ($-$)-discodermolide (1), antipode of po...
An approach to the asymmetric synthesis of fragments corresponding to C1---C7 and C15---C24 of (+)-d...
Coupling Of C9-14 (4) and C15-21 (5a) fragments to produce the cis-trisubstituted olefin was achieve...
The dissertation contained herein describes synthetic studies of (+)-discodermolide (1), a deep-sea ...
In 1990, the natural product discodermolide was isolated from a marine sponge and later found to hav...
The application of the [2,3] Wittig rearrangement to the total synthesis of (+)-discodermolide is th...
International audienceThis account describes an efficient and modulable total synthesis of (+)-disco...
Discodermolide was discovered in 1990 and with its discovery set off an expansive\ud medicinal chemi...
[structure: see text] Four truncated analogues of the natural product discodermolide were synthesize...
A novel total synthesis of the complex polyketide (+)-discodermolide, a promising anticancer agent o...
New (+)-discodermolide analogs were designed by Professor Mark A. Lipton using FEP calculations to s...
Thesis advisor: James P. Morken(+)-Discodermolide is a marine natural product and is one of the most...
[structure: see text] Two hybrid analogues of discodermolide and dictyostatin (3, 26) have been desi...