Background: Endocrine dysfunction is not uncommon complication in patients with transfusion dependent thalassemia and is thought to occur as a consequence of excessive iron overload. The main objective of this study is to determine the frequency of adrenal insufficiency in patients with thalassemia major and thalassemia intermediate. Methods: This cross-sectional study was done at the Shiraz University of Medical Sciences, Shiraz, Southern Iran, in 2013. One hundred and ninety patients were divided into two groups; thalassemia major(TM) and thalassemia intermediate (TI) groups. We measured 8 AM serum cortisol, ACTH and ferritin concentrations in all patients. Results: The mean age of the TM and TI group were 22.5±5.7 and 23.8±6 years, resp...
Objective: Despite regular transfusions and iron-chelation therapies, endocrine complications still ...
Beta- thalassemia major is a type of inherited blood disorder, characterized by impaired synthesis...
Purpose: Beta-thalassemia major is a severe, congenital hematological disorder and, if untreated, le...
Abstract. Background. Endocrine dysfunction is not uncommon complication in patients with transfusio...
Objective: We previously described in young thalassaemic patients an altered cortisol and ACTH respo...
Background: Thalassemia Major (TM) is a complex pathology that needs a highly skilled approach. Endo...
Better transfusion and chelation regimens have changed the natural history of \u3b2-thalassaemia fro...
Endocrine complications in patients with thalassemia major in developing countries may be frequent d...
Abstract. Introduction: It is well known that the older generation of adult TM patients has a higher...
Background: Thalassemia refers to a group of genetically inherited diseases characterized by decreas...
OBJECTIVE Thalassaemia major is a common and serious medical problem, worldwide. However, there are ...
Background: In March 2015, the International Network of Clinicians for Endocrinopathies in Thalassem...
Introduction: In March 2015, the International Network of Clinicians for Endocrinopathies in Thalass...
Introduction: Thalassaemia major is an inherited haemoglobinopathy characterised by chronic anaemia....
Thalassemia major is a transfusion dependent genetically inherited haematological disorder that coul...
Objective: Despite regular transfusions and iron-chelation therapies, endocrine complications still ...
Beta- thalassemia major is a type of inherited blood disorder, characterized by impaired synthesis...
Purpose: Beta-thalassemia major is a severe, congenital hematological disorder and, if untreated, le...
Abstract. Background. Endocrine dysfunction is not uncommon complication in patients with transfusio...
Objective: We previously described in young thalassaemic patients an altered cortisol and ACTH respo...
Background: Thalassemia Major (TM) is a complex pathology that needs a highly skilled approach. Endo...
Better transfusion and chelation regimens have changed the natural history of \u3b2-thalassaemia fro...
Endocrine complications in patients with thalassemia major in developing countries may be frequent d...
Abstract. Introduction: It is well known that the older generation of adult TM patients has a higher...
Background: Thalassemia refers to a group of genetically inherited diseases characterized by decreas...
OBJECTIVE Thalassaemia major is a common and serious medical problem, worldwide. However, there are ...
Background: In March 2015, the International Network of Clinicians for Endocrinopathies in Thalassem...
Introduction: In March 2015, the International Network of Clinicians for Endocrinopathies in Thalass...
Introduction: Thalassaemia major is an inherited haemoglobinopathy characterised by chronic anaemia....
Thalassemia major is a transfusion dependent genetically inherited haematological disorder that coul...
Objective: Despite regular transfusions and iron-chelation therapies, endocrine complications still ...
Beta- thalassemia major is a type of inherited blood disorder, characterized by impaired synthesis...
Purpose: Beta-thalassemia major is a severe, congenital hematological disorder and, if untreated, le...