A randomized trial of intraarterial treatment for acute ischemic stroke
- Berkhemer, O.A.
- Fransen, P.S.
- Beumer, D.
- Berg, L.A. van den
- Lingsma, H.F.
- Yoo, A.J.
- Schonewille, W.J.
- Vos, J.A.
- Nederkoorn, P.J.
- Wermer, M.J.
- Walderveen, M.A. van
- Staals, J.
- Hofmeijer, J.
- Oostayen, J.A.
- Lycklama a Nijeholt, G.J.
- Boiten, J.
- Brouwer, P.A.
- Emmer, B.J.
- Bruijn, S.F.T.M. de
- Dijk, L.C. van
- Kappelle, L.J.
- Lo, R.H.
- Dijk, E.J. van
- Vries, J. de
- Kort, P.L. de
- Rooij, W.J. van
- Berg, J.S.
- Hasselt, B.A. van
- Aerden, L.A.
- Dallinga, R.J.
- Visser, M.C
- Bot, J.C.
- Vroomen, P.C.
- Eshghi, O.
- Schreuder, T.H.A.
- Heijboer, R.J.
- Keizer, K.
- Tielbeek, A.V.
- Hertog, H.M. den
- Gerrits, D.G.
- Berg-Vos, R.M. van den
- Karas, G.B.
- Steyerberg, E.W.
- Flach, H.Z.
- Marquering, H.A.
- Sprengers, M.E.
- Jenniskens, S.F.M.
- Beenen, L.F.
- Berg, R. van den
- Koudstaal, P.J.
- Zwam, W.H. van
- Roos, Y.B.
- Lugt, A. van der
- Oostenbrugge, R.J. van
- Majoie, C.B.
- Dippel, D.W.
DOIAbstract
Contains fulltext : 153000.pdf (publisher's version ) (Open Access)BACKGROUND: In patients with acute ischemic stroke caused by a proximal intracranial arterial occlusion, intraarterial treatment is highly effective for emergency revascularization. However, proof of a beneficial effect on functional outcome is lacking. METHODS: We randomly assigned eligible patients to either intraarterial treatment plus usual care or usual care alone. Eligible patients had a proximal arterial occlusion in the anterior cerebral circulation that was confirmed on vessel imaging and that could be treated intraarterially within 6 hours after symptom onset. The primary outcome was the modified Rankin scale score at 90 days; this categorical sca...
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