Isolation and identification of the human homolog of a new p53-binding protein, Mdmx

MDM2 and MDMX bind and stabilize the p53-related protein p73

Ongkeko, Weg M.
Wang, Xiao Qi
Siu, Wai Yi
Lau, Anita W.S.
Yamashita, Katsumi
Harris, Adrian L.
Cox, Lynne S.
Poon, Randy Y.C.

August 1999

AbstractThe p53 gene encodes one of the most important tumor suppressors in human cells and undergoe...

Optimal Affinity Enhancement by a Conserved Flexible Linker Controls p53 Mimicry in MdmX

Borcherds, Wade
Becker, Andreas
Chen, Lihong
Chen, Jiandong
Chemes, Lucia Beatriz
Daughdrill, Gary W.

May 2017

MdmX contains an intramolecular binding motif that mimics the binding of the p53 tumor suppressor. T...

Identification of a Human cDNA Sequence Which Encodes a Novel Membrane-associated Protein Containing a Zinc Metalloprotease Motif

Toshio Kitamura
Hidetoshi Kumagai

January 2003

We report the cloning and characterization of a human cDNA predicted to encode a novel hydrophobic p...

Isolation and identification of the human homolog of a new p53-binding protein, Mdmx

Shvarts, A.
Bazuine, M.
Dekker, P.
Ramos, Y.F.M.
Steegenga, W.T.
Merckx, G.F.M.
Ham, R. van
Houven van Oordt, W. van der
Eb, A.J. van der
Jochemsen, A.G.

January 1997

Contains fulltext : 26148___.PDF (publisher's version ) (Open Access)Oude waarde d...

DNA Damage-Induced Phosphorylation of MdmX at Serine 367 Activates p53 by Targeting MdmX for

Aart G. Jochemsen
Yoichi Taya

January 2005

Understanding how p53 activity is regulated is crucial in elucidating mechanisms of cellular defense...

Modulators of the p53-MDM2 interaction : search for MDM2 interactors using structural guidance

Lin, Jianqing

January 2014

The interaction between MDM2 and p53 is essential for several cellular events, including cell growth...

The MDM2 oncoprotein interacts with the structurally related MDMX protein: Identification and analysis

Sharp, Darcie

January 2000

It is widely accepted that the MDM2 oncoprotein is an inhibitor of the p53 tumor suppressor, via the...

Mdm2 and MdmX partner to regulate p53

Wang, Xinjiang
Jiang, Xuejun

May 2012

AbstractMdm2 regulates the stability, translation, subcellular localization and transcriptional acti...

MDM2 and MDMX bind and stabilize the p53-related protein p73

Wang, X
Lau, AWS
Yamashita, K
Harris, AL
Ongkeko, WM
Cox, LS
Poon, RYC
Siu, WY

January 1999

The p53 gene encodes one of the most important tumor suppressors in human cells and undergoes freque...

Additional file 12: Figure S12. of A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein–protein interactions identifies a novel putative Mdm2-binding site in p53

Jin Wong (3600983)
Mohammad Alfatah (4584019)
Mei Sin (4584016)
Hong Sim (4584013)
Chandra Verma (23219)
David Lane (311623)
Prakash Arumugam (303310)

November 2017

The conserved Segment 1 in p53’s DNA-binding domain promotes interaction with Mdm2. Amounts of Mdm2-...

RESEARCH Amplification of Mdmx an M

August 2015

Full list of author information is available at the end of the articleagainst cancer. The tumor prot...

SEE PROFILE

Xinjiang Wang
Available From Xinjiang Wang

January 2016

lity t p lt ti n th do as a substrate of Mdm2/MdmX E3 complex. The insufficiency of Mdm2 for p53 pol...

Amplification Of A Gene Encoding A P53-associated Protein In Human Sarcomas

Oliner, J. D.
Kinzler, Kenneth W.
Meltzer, Paul S.
George, D. L.
Vogelstein, Bert

July 1992

DESPITE extensive data linking mutations in the p53 gene to human tumorigenesis 1, little is known a...

Native PAGE to study the interaction between the oncosuppressor p53 and its protein ligands

Lamberti A.
Sgammato R.
Desiderio D.
Punzo C.
Raimo G.
NOVELLINO, ETTORE
CAROTENUTO, ALFONSO
Masullo M.

January 2015

In the present study, we investigated a new approach for studying the interaction between p53 and MD...

Characterization of genome-wide p53-binding sites upon stress response

Smeenk, L.
Heeringen, S.J. van
Koeppel, M.
Driel, M.A. van
Bartels, S.J.J.
Akkers, R.C.
Denissov, S.
Stunnenberg, H.G.
Lohrum, M.

January 2008

Contains fulltext : 71904.pdf (publisher's version ) (Open Access)6 p

MDM2 and MDMX bind and stabilize the p53-related protein p73

Ongkeko, Weg M.
Wang, Xiao Qi
Siu, Wai Yi
Lau, Anita W.S.
Yamashita, Katsumi
Harris, Adrian L.
Cox, Lynne S.
Poon, Randy Y.C.

August 1999

AbstractThe p53 gene encodes one of the most important tumor suppressors in human cells and undergoe...

Optimal Affinity Enhancement by a Conserved Flexible Linker Controls p53 Mimicry in MdmX

Borcherds, Wade
Becker, Andreas
Chen, Lihong
Chen, Jiandong
Chemes, Lucia Beatriz
Daughdrill, Gary W.

May 2017

MdmX contains an intramolecular binding motif that mimics the binding of the p53 tumor suppressor. T...

Identification of a Human cDNA Sequence Which Encodes a Novel Membrane-associated Protein Containing a Zinc Metalloprotease Motif

Toshio Kitamura
Hidetoshi Kumagai

January 2003

We report the cloning and characterization of a human cDNA predicted to encode a novel hydrophobic p...

Isolation and identification of the human homolog of a new p53-binding protein, Mdmx

Shvarts, A.
Bazuine, M.
Dekker, P.
Ramos, Y.F.M.
Steegenga, W.T.
Merckx, G.F.M.
Ham, R. van
Houven van Oordt, W. van der
Eb, A.J. van der
Jochemsen, A.G.

January 1997

Contains fulltext : 26148___.PDF (publisher's version ) (Open Access)Oude waarde d...

DNA Damage-Induced Phosphorylation of MdmX at Serine 367 Activates p53 by Targeting MdmX for

Aart G. Jochemsen
Yoichi Taya

January 2005

Understanding how p53 activity is regulated is crucial in elucidating mechanisms of cellular defense...

Modulators of the p53-MDM2 interaction : search for MDM2 interactors using structural guidance

Lin, Jianqing

January 2014

The interaction between MDM2 and p53 is essential for several cellular events, including cell growth...

The MDM2 oncoprotein interacts with the structurally related MDMX protein: Identification and analysis

Sharp, Darcie

January 2000

It is widely accepted that the MDM2 oncoprotein is an inhibitor of the p53 tumor suppressor, via the...

Mdm2 and MdmX partner to regulate p53

Wang, Xinjiang
Jiang, Xuejun

May 2012

AbstractMdm2 regulates the stability, translation, subcellular localization and transcriptional acti...

MDM2 and MDMX bind and stabilize the p53-related protein p73

Wang, X
Lau, AWS
Yamashita, K
Harris, AL
Ongkeko, WM
Cox, LS
Poon, RYC
Siu, WY

January 1999

The p53 gene encodes one of the most important tumor suppressors in human cells and undergoes freque...

Additional file 12: Figure S12. of A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein–protein interactions identifies a novel putative Mdm2-binding site in p53

Jin Wong (3600983)
Mohammad Alfatah (4584019)
Mei Sin (4584016)
Hong Sim (4584013)
Chandra Verma (23219)
David Lane (311623)
Prakash Arumugam (303310)

November 2017

The conserved Segment 1 in p53’s DNA-binding domain promotes interaction with Mdm2. Amounts of Mdm2-...

RESEARCH Amplification of Mdmx an M

August 2015

Full list of author information is available at the end of the articleagainst cancer. The tumor prot...

SEE PROFILE

Xinjiang Wang
Available From Xinjiang Wang

January 2016

lity t p lt ti n th do as a substrate of Mdm2/MdmX E3 complex. The insufficiency of Mdm2 for p53 pol...

Amplification Of A Gene Encoding A P53-associated Protein In Human Sarcomas

Oliner, J. D.
Kinzler, Kenneth W.
Meltzer, Paul S.
George, D. L.
Vogelstein, Bert

July 1992

DESPITE extensive data linking mutations in the p53 gene to human tumorigenesis 1, little is known a...

Native PAGE to study the interaction between the oncosuppressor p53 and its protein ligands

Lamberti A.
Sgammato R.
Desiderio D.
Punzo C.
Raimo G.
NOVELLINO, ETTORE
CAROTENUTO, ALFONSO
Masullo M.

January 2015

In the present study, we investigated a new approach for studying the interaction between p53 and MD...

Characterization of genome-wide p53-binding sites upon stress response

Smeenk, L.
Heeringen, S.J. van
Koeppel, M.
Driel, M.A. van
Bartels, S.J.J.
Akkers, R.C.
Denissov, S.
Stunnenberg, H.G.
Lohrum, M.

January 2008

Contains fulltext : 71904.pdf (publisher's version ) (Open Access)6 p

MDM2 and MDMX bind and stabilize the p53-related protein p73

Ongkeko, Weg M.
Wang, Xiao Qi
Siu, Wai Yi
Lau, Anita W.S.
Yamashita, Katsumi
Harris, Adrian L.
Cox, Lynne S.
Poon, Randy Y.C.

August 1999

AbstractThe p53 gene encodes one of the most important tumor suppressors in human cells and undergoe...

Optimal Affinity Enhancement by a Conserved Flexible Linker Controls p53 Mimicry in MdmX

Borcherds, Wade
Becker, Andreas
Chen, Lihong
Chen, Jiandong
Chemes, Lucia Beatriz
Daughdrill, Gary W.

May 2017

MdmX contains an intramolecular binding motif that mimics the binding of the p53 tumor suppressor. T...

Identification of a Human cDNA Sequence Which Encodes a Novel Membrane-associated Protein Containing a Zinc Metalloprotease Motif

Toshio Kitamura
Hidetoshi Kumagai

January 2003

We report the cloning and characterization of a human cDNA predicted to encode a novel hydrophobic p...

Isolation and identification of the human homolog of a new p53-binding protein, Mdmx

Abstract

Extracted data

Isolation and identification of the human homolog of a new p53-binding protein, Mdmx

Abstract

Extracted data

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