The inhibitory receptor FcgammaRII reduces joint inflammation and destruction in experimental immune complex-mediated arthritides not only by inhibition of FcgammaRI/III but also by efficient clearance and endocytosis of immune complexes.

Role of activatory Fc gamma RI and Fc gamma RIII and inhibitory Fc gamma RII in inflammation and cartilage destruction during experimental antigen-induced arthritis.

Lent, P.L.E.M. van
Nabbe, K.C.A.M.
Blom, A.B.
Holthuysen, A.E.M.
Sloetjes, A.W.
Putte, L.B.A. van de
Verbeek, S.
Berg, W.B. van den

January 2001

IgG-containing immune complexes, which are found in most RA joints, communicate with hematopoietic c...

FcgammaRIII engagement provides activating signals to NKT cells in antibody-induced joint inflammation

Kim, H. Y.
Kim, S.
Chung, D. H.

August 2006

NKT cells promote antibody-induced arthritis, but the mechanism by which NKT cells are activated in ...

Immune complex-induced inhibition of osteoclastogenesis is mediated via activating but not inhibitory Fcgamma receptors on myeloid precursor cells

Grevers, L.C.
Vries, T.J. de
Everts, V.
Verbeek, J.S.
Berg, W.B. van den
Lent, P.L. van

January 2013

OBJECTIVE: To investigate the role of Fcgamma receptors (FcgammaRs) in osteoclastogenesis and osteoc...

The inhibitory receptor FcgammaRII reduces joint inflammation and destruction in experimental immune complex-mediated arthritides not only by inhibition of FcgammaRI/III but also by efficient clearance and endocytosis of immune complexes.

Lent, P.L.E.M. van
Nabbe, K.C.A.M.
Boross, P.
Blom, A.B.
Roth, J.
Holthuysen, A.E.M.
Sloetjes, A.W.
Verbeek, S.
Berg, W.B. van den

January 2003

Studies of FcgammaRII-/- mice identified the inhibitory function of this receptor in joint inflammat...

Fcgamma receptors directly mediate cartilage, but not bone, destruction in murine antigen-induced arthritis: uncoupling of cartilage damage from bone erosion and joint inflammation.

Lent, P.L.E.M. van
Grevers, L.C.
Lubberts, E.
Vries, T.J. de
Nabbe, K.C.A.M.
Verbeek, S.
Oppers-Walgreen, B.
Sloetjes, A.W.
Blom, A.B.
Berg, W.B. van den

January 2006

OBJECTIVE: To determine the relationship between synovial inflammation and the concomitant occurrenc...

FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection.

Ioan-Facsinay, A.
Kimpe, S.J. de
Hellwig, S.M.
Lent, P.L.E.M. van
Hofhuis, F.M.
Ojik, H.H. van
Sedlik, C.
Silveira, S.A. da
Gerber, J.
Jong, Y.F. de
Roozendaal, R.
Aarden, L.A.
Berg, W.B. van den
Saito, T.
Mosser, D.
Amigorena, S.
Izui, S.
Ommen, G.J.B. van
Vugt, M. van
Winkel, J.G.J. van de
Verbeek, J.S.

January 2002

Item does not contain fulltextThe high-affinity receptor for IgG, FcgammaRI, shares its capacity to ...

FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection

Ioan-Facsinay, A.
de Kimpe, S. J.
Hellwig, S. M.
van Lent, P. L.
Hofhuis, F. M.
van Ojik, H. H.
Sedlik, C.
da Silveira, S. A.
Gerber, J.
de Jong, Y. F.
Roozendaal, R.
Aarden, L. A.
van den Berg, W. B.
Saito, Takashi
Mosser, D.
Amigorena, S.
Izui, Shozo
van Ommen, G. J.
van Vugt, M.
van de Winkel, J. G.
Verbeek, J. S.

January 2002

The high-affinity receptor for IgG, FcgammaRI, shares its capacity to bind IgG2a immune complexes (I...

Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII.

Boross, P.
Lent, P.L.E.M. van
Martin-Ramirez, J.
Kaa, J. van der
Mulder, M.H.
Claassens, J.W.
Berg, W.B. van den
Arandhara, V.L.
Verbeek, J.S.

January 2008

Contains fulltext : 69780.pdf (publisher's version ) (Closed access)Fc receptors f...

FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection.

Ioan-Facsinay, A.
Kimpe, S.J. de
Hellwig, S.M.
Lent, P.L.E.M. van
Hofhuis, F.M.
Ojik, H.H. van
Sedlik, C.
Silveira, S.A. da
Gerber, J.
Jong, Y.F. de
Roozendaal, R.
Aarden, L.A.
Berg, W.B. van den
Saito, T.
Mosser, D.
Amigorena, S.
Izui, S.
Ommen, G.J.B. van
Vugt, M. van
Winkel, J.G.J. van de
Verbeek, J.S.

January 2002

The high-affinity receptor for IgG, FcgammaRI, shares its capacity to bind IgG2a immune complexes (I...

Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII.

Boross, P.
Lent, P.L.E.M. van
Martin-Ramirez, J.
Kaa, J. van der
Mulder, M.H.
Claassens, J.W.
Berg, W.B. van den
Arandhara, V.L.
Verbeek, J.S.

January 2008

Fc receptors for IgG (FcgammaR) have been implicated in the development of arthritis. However, the p...

Joint inflammation and chondrocyte death become independent of Fcgamma receptor type III by local overexpression of interferon-gamma during immune complex-mediated arthritis.

Nabbe, K.C.A.M.
Boross, P.
Holthuysen, A.E.M.
Sloetjes, A.W.
Kolls, J.
Verbeek, S.
Lent, P.L.E.M. van
Berg, W.B. van den

January 2005

OBJECTIVE: It has previously been shown that the onset and the degree of joint inflammation during i...

Skewed balance in basal expression and regulation of activating v inhibitory Fcgamma receptors in macrophages of collagen induced arthritis sensitive mice.

Blom, A.B.
Lent, P.L.E.M. van
Holthuysen, A.E.M.
Jacobs, C.W.M.
Berg, W.B. van den

January 2003

BACKGROUND: Recently, it has been found that collagen type II arthritis susceptible mouse strains ar...

Joint inflammation and chondrocyte death become independent of Fcgamma receptor type III by local overexpression of interferon-gamma during immune complex-mediated arthritis.

Nabbe, K.C.A.M.
Boross, P.
Holthuysen, A.E.M.
Sloetjes, A.W.
Kolls, J.
Verbeek, S.
Lent, P.L.E.M. van
Berg, W.B. van den

January 2005

Item does not contain fulltextOBJECTIVE: It has previously been shown that the onset and the degree ...

FcgammaRI up-regulation induced by local adenoviral-mediated interferon-gamma production aggravates chondrocyte death during immune complex-mediated arthritis.

Nabbe, K.C.A.M.
Lent, P.L.E.M. van
Holthuysen, A.E.M.
Kolls, J.
Verbeek, S.
Berg, W.B. van den

January 2003

Using various FcgammaR-deficient mice, we have obtained suggestive evidence that FcgammaRI on macrop...

Role of activatory Fc gamma RI and Fc gamma RIII and inhibitory Fc gamma RII in inflammation and cartilage destruction during experimental antigen-induced arthritis.

Lent, P.L.E.M. van
Nabbe, K.C.A.M.
Blom, A.B.
Holthuysen, A.E.M.
Sloetjes, A.W.
Putte, L.B.A. van de
Verbeek, S.
Berg, W.B. van den

January 2001

Item does not contain fulltextIgG-containing immune complexes, which are found in most RA joints, co...

Role of activatory Fc gamma RI and Fc gamma RIII and inhibitory Fc gamma RII in inflammation and cartilage destruction during experimental antigen-induced arthritis.

Lent, P.L.E.M. van
Nabbe, K.C.A.M.
Blom, A.B.
Holthuysen, A.E.M.
Sloetjes, A.W.
Putte, L.B.A. van de
Verbeek, S.
Berg, W.B. van den

January 2001

IgG-containing immune complexes, which are found in most RA joints, communicate with hematopoietic c...

FcgammaRIII engagement provides activating signals to NKT cells in antibody-induced joint inflammation

Kim, H. Y.
Kim, S.
Chung, D. H.

August 2006

NKT cells promote antibody-induced arthritis, but the mechanism by which NKT cells are activated in ...

Immune complex-induced inhibition of osteoclastogenesis is mediated via activating but not inhibitory Fcgamma receptors on myeloid precursor cells

Grevers, L.C.
Vries, T.J. de
Everts, V.
Verbeek, J.S.
Berg, W.B. van den
Lent, P.L. van

January 2013

OBJECTIVE: To investigate the role of Fcgamma receptors (FcgammaRs) in osteoclastogenesis and osteoc...

The inhibitory receptor FcgammaRII reduces joint inflammation and destruction in experimental immune complex-mediated arthritides not only by inhibition of FcgammaRI/III but also by efficient clearance and endocytosis of immune complexes.

Lent, P.L.E.M. van
Nabbe, K.C.A.M.
Boross, P.
Blom, A.B.
Roth, J.
Holthuysen, A.E.M.
Sloetjes, A.W.
Verbeek, S.
Berg, W.B. van den

January 2003

Studies of FcgammaRII-/- mice identified the inhibitory function of this receptor in joint inflammat...

Fcgamma receptors directly mediate cartilage, but not bone, destruction in murine antigen-induced arthritis: uncoupling of cartilage damage from bone erosion and joint inflammation.

Lent, P.L.E.M. van
Grevers, L.C.
Lubberts, E.
Vries, T.J. de
Nabbe, K.C.A.M.
Verbeek, S.
Oppers-Walgreen, B.
Sloetjes, A.W.
Blom, A.B.
Berg, W.B. van den

January 2006

OBJECTIVE: To determine the relationship between synovial inflammation and the concomitant occurrenc...

FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection.

Ioan-Facsinay, A.
Kimpe, S.J. de
Hellwig, S.M.
Lent, P.L.E.M. van
Hofhuis, F.M.
Ojik, H.H. van
Sedlik, C.
Silveira, S.A. da
Gerber, J.
Jong, Y.F. de
Roozendaal, R.
Aarden, L.A.
Berg, W.B. van den
Saito, T.
Mosser, D.
Amigorena, S.
Izui, S.
Ommen, G.J.B. van
Vugt, M. van
Winkel, J.G.J. van de
Verbeek, J.S.

January 2002

Item does not contain fulltextThe high-affinity receptor for IgG, FcgammaRI, shares its capacity to ...

FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection

Ioan-Facsinay, A.
de Kimpe, S. J.
Hellwig, S. M.
van Lent, P. L.
Hofhuis, F. M.
van Ojik, H. H.
Sedlik, C.
da Silveira, S. A.
Gerber, J.
de Jong, Y. F.
Roozendaal, R.
Aarden, L. A.
van den Berg, W. B.
Saito, Takashi
Mosser, D.
Amigorena, S.
Izui, Shozo
van Ommen, G. J.
van Vugt, M.
van de Winkel, J. G.
Verbeek, J. S.

January 2002

The high-affinity receptor for IgG, FcgammaRI, shares its capacity to bind IgG2a immune complexes (I...

Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII.

Boross, P.
Lent, P.L.E.M. van
Martin-Ramirez, J.
Kaa, J. van der
Mulder, M.H.
Claassens, J.W.
Berg, W.B. van den
Arandhara, V.L.
Verbeek, J.S.

January 2008

Contains fulltext : 69780.pdf (publisher's version ) (Closed access)Fc receptors f...

FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection.

Ioan-Facsinay, A.
Kimpe, S.J. de
Hellwig, S.M.
Lent, P.L.E.M. van
Hofhuis, F.M.
Ojik, H.H. van
Sedlik, C.
Silveira, S.A. da
Gerber, J.
Jong, Y.F. de
Roozendaal, R.
Aarden, L.A.
Berg, W.B. van den
Saito, T.
Mosser, D.
Amigorena, S.
Izui, S.
Ommen, G.J.B. van
Vugt, M. van
Winkel, J.G.J. van de
Verbeek, J.S.

January 2002

The high-affinity receptor for IgG, FcgammaRI, shares its capacity to bind IgG2a immune complexes (I...

Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII.

Boross, P.
Lent, P.L.E.M. van
Martin-Ramirez, J.
Kaa, J. van der
Mulder, M.H.
Claassens, J.W.
Berg, W.B. van den
Arandhara, V.L.
Verbeek, J.S.

January 2008

Fc receptors for IgG (FcgammaR) have been implicated in the development of arthritis. However, the p...

Joint inflammation and chondrocyte death become independent of Fcgamma receptor type III by local overexpression of interferon-gamma during immune complex-mediated arthritis.

Nabbe, K.C.A.M.
Boross, P.
Holthuysen, A.E.M.
Sloetjes, A.W.
Kolls, J.
Verbeek, S.
Lent, P.L.E.M. van
Berg, W.B. van den

January 2005

OBJECTIVE: It has previously been shown that the onset and the degree of joint inflammation during i...

Skewed balance in basal expression and regulation of activating v inhibitory Fcgamma receptors in macrophages of collagen induced arthritis sensitive mice.

Blom, A.B.
Lent, P.L.E.M. van
Holthuysen, A.E.M.
Jacobs, C.W.M.
Berg, W.B. van den

January 2003

BACKGROUND: Recently, it has been found that collagen type II arthritis susceptible mouse strains ar...

Joint inflammation and chondrocyte death become independent of Fcgamma receptor type III by local overexpression of interferon-gamma during immune complex-mediated arthritis.

Nabbe, K.C.A.M.
Boross, P.
Holthuysen, A.E.M.
Sloetjes, A.W.
Kolls, J.
Verbeek, S.
Lent, P.L.E.M. van
Berg, W.B. van den

January 2005

Item does not contain fulltextOBJECTIVE: It has previously been shown that the onset and the degree ...

FcgammaRI up-regulation induced by local adenoviral-mediated interferon-gamma production aggravates chondrocyte death during immune complex-mediated arthritis.

Nabbe, K.C.A.M.
Lent, P.L.E.M. van
Holthuysen, A.E.M.
Kolls, J.
Verbeek, S.
Berg, W.B. van den

January 2003

Using various FcgammaR-deficient mice, we have obtained suggestive evidence that FcgammaRI on macrop...

Role of activatory Fc gamma RI and Fc gamma RIII and inhibitory Fc gamma RII in inflammation and cartilage destruction during experimental antigen-induced arthritis.

Lent, P.L.E.M. van
Nabbe, K.C.A.M.
Blom, A.B.
Holthuysen, A.E.M.
Sloetjes, A.W.
Putte, L.B.A. van de
Verbeek, S.
Berg, W.B. van den

January 2001

Item does not contain fulltextIgG-containing immune complexes, which are found in most RA joints, co...

Role of activatory Fc gamma RI and Fc gamma RIII and inhibitory Fc gamma RII in inflammation and cartilage destruction during experimental antigen-induced arthritis.

Lent, P.L.E.M. van
Nabbe, K.C.A.M.
Blom, A.B.
Holthuysen, A.E.M.
Sloetjes, A.W.
Putte, L.B.A. van de
Verbeek, S.
Berg, W.B. van den

January 2001

IgG-containing immune complexes, which are found in most RA joints, communicate with hematopoietic c...

FcgammaRIII engagement provides activating signals to NKT cells in antibody-induced joint inflammation

Kim, H. Y.
Kim, S.
Chung, D. H.

August 2006

NKT cells promote antibody-induced arthritis, but the mechanism by which NKT cells are activated in ...

Immune complex-induced inhibition of osteoclastogenesis is mediated via activating but not inhibitory Fcgamma receptors on myeloid precursor cells

Grevers, L.C.
Vries, T.J. de
Everts, V.
Verbeek, J.S.
Berg, W.B. van den
Lent, P.L. van

January 2013

OBJECTIVE: To investigate the role of Fcgamma receptors (FcgammaRs) in osteoclastogenesis and osteoc...

The inhibitory receptor FcgammaRII reduces joint inflammation and destruction in experimental immune complex-mediated arthritides not only by inhibition of FcgammaRI/III but also by efficient clearance and endocytosis of immune complexes.

Abstract

Extracted data

The inhibitory receptor FcgammaRII reduces joint inflammation and destruction in experimental immune complex-mediated arthritides not only by inhibition of FcgammaRI/III but also by efficient clearance and endocytosis of immune complexes.

Abstract

Extracted data

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