A polymorphic enhancer near grem1 influences bowel cancer risk through differential cdx2 and tcf7l2 binding

The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression.

Pittman, Alan M
Naranjo, Silvia
Webb, Emily
Broderick, Peter
Lips, Esther H
van Wezel, Tom
Morreau, Hans
Sullivan, Kate
Fielding, Sarah
Twiss, Philip
Vijayakrishnan, Jayaram
Casares, Fernando
Qureshi, Mobshra
Gómez-Skarmeta, José Luis
Houlston, Richard S

January 2009

Recent genome-wide scans for colorectal cancer (CRC) have revealed the SMAD7 (mothers against decape...

Genetic polymorphism in UDP-glucuronosyltransferase 2B7 and colorectal cancer risk.

Logt, E.M.J. van der
Morsche, R.H.M. te
Groenendaal, N.
Roelofs, H.M.J.
Metz, M. de
Stappen, J.W. van der
Nagengast, F.M.
Peters, W.H.M.

January 2009

Item does not contain fulltextColorectal cancer (CRC) is one of the most common malignancies in the ...

Regulatory cytokine gene polymorphisms and risk of colorectal carcinoma

A. Crivello
A. Giacalone
M. Vaglica
L. Scola
G.I. Forte
M.C. Macaluso
C. Raimondi
L. Di Noto
A. Bongiovanni
A. Accardo
G. Candore
L. Palmeri
Roberto Verna
C. Caruso
D. Lio
S. Palmeri

January 2006

It is well established that cancer arises in chronically inflamed tissue, and this is particularly n...

A Polymorphic Enhancer near GREM1 Influences Bowel Cancer Risk through Differential CDX2 and TCF7L2 Binding

Lewis, Annabelle
Freeman-Mills, Luke
de la Calle-Mustienes, Elisa
Giráldez-Pérez, Rosa María
Davis, Hayley
Jaeger, Emma
Becker, Martin
Hubner, Nina C.
Nguyen, Luan N.
Zeron-Medina, Jorge
Bond, Gareth
Stunnenberg, Hendrik G.
Carvajal, Jaime J.
Gomez-Skarmeta, Jose Luis
Leedham, Simon
Tomlinson, Ian

August 2014

SummaryA rare germline duplication upstream of the bone morphogenetic protein antagonist GREM1 cause...

A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding

Calle-Mustienes, Elisa de la
Giráldez-Pérez, Rosa María
Carvajal, Jaime J.
Gómez-Skarmeta, José Luis
Tomlinson, Ian

January 2016

Under a Creative Commons license.-- et al.A rare germline duplication upstream of the bone morphogen...

A polymorphic enhancer near GREM1 influences bowel cancer risk through diifferential CDX2 and TCF7L2 binding

Lewis, A.
Freeman-Mills, L.
de la Calle-Mustienes, E.
Giráldez-Pérez, R.
Davis, H.
Jaeger, E.
Becker, M.
Hubner, N.
Nguyen, L.
Zeron-Medina, J.
Bond, G.
Stunnenberg, H.
Carvajal, J.
Gomez-Skarmeta, J.
Leedham, S.
Tomlinson, I.

January 2014

A rare germline duplication upstream of the bone morphogenetic protein antagonist GREM1 causes a Men...

A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding.

Lewis, A
Freeman-Mills, L
de la Calle-Mustienes, E
Giráldez-Pérez, RM
Davis, H
Jaeger, E
Becker, M
Hubner, NC
Nguyen, LN
Zeron-Medina, J
Bond, G
Stunnenberg, HG
Carvajal, JJ
Gomez-Skarmeta, JL
Leedham, S
Tomlinson, I

August 2014

A rare germline duplication upstream of the bone morphogenetic protein antagonist GREM1 causes a Men...

Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk.

Logt, E.M.J. van der
Bergevoet, S.M.
Roelofs, H.M.J.
Hooijdonk, Z. van
Morsche, R.H.M. te
Wobbes, T.
Kok, J.B. de
Nagengast, F.M.
Peters, W.H.M.

January 2004

Contains fulltext : 58357.pdf (publisher's version ) (Closed access)Colorectal can...

Polymorphisms in the Insulin-Like Growth Factor Axis Are Associated with Gastrointestinal Cancer

Jennie Ong
Jody Salomon
Rene H. M. Te Morsche
Hennie M. J. Roelofs
Ben J. M. Witteman
Polat Dura
Martin Lacko
Wilbert H. M. Peters

September 2016

The following full text is a publisher's version. For additional information about this publica...

The heterogeneity of genetic predisposition to early-onset colorectal cancer

Hahn, M.M.

January 2016

Contains fulltext : 157676.pdf (publisher's version ) (Open Access)Colorectal canc...

The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression

Naranjo, Silvia
Casares, Fernando
Gómez-Skarmeta, José Luis
Houlston, Richard S.

April 2009

7 páginas, 4 figuras, 1 tabla.-- et al.Recent genome-wide scans for colorectal cancer (CRC) have rev...

Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1.

Jaeger, E
Leedham, S
Lewis, A
Segditsas, S
Becker, M
Cuadrado, PR
Davis, H
Kaur, K
Heinimann, K
Howarth, K
East, J
Taylor, J
Thomas, H
Tomlinson, I

June 2012

Hereditary mixed polyposis syndrome (HMPS) is characterized by apparent autosomal dominant inheritan...

Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1

Jaeger, E.
Leedham, S.
Lewis, A.
Segditsas, S.
Becker, M.
Rodenas-Cuadrado, P.
Davis, H.
Kaur, K.
Heinimann, K.
Howarth, K.
East, J.
Taylor, J.
Thomas, H.
Tomlinson, I.

January 2012

Hereditary mixed polyposis syndrome (HMPS) is characterized by apparent autosomal dominant inheritan...

TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions

Verzi, M. P.
Hatzis, P.
Sulahian, R.
Philips, J.
Schuijers, J.
Shin, H.D.
Freed, E.
Lynch, J. P.
Dang, D. T.
Brown, M.
Clevers, H.
Liu, X. S.
Shivdasani, R. A.

January 2010

Surprisingly few pathways signal between cells, raising questions about mechanisms for tissue-specif...

Molecular alterations underlying genetic predisposition to gastrointestinal cancer

Vogelaar, I.P.

January 2015

Contains fulltext : 140189.pdf (publisher's version ) (Open Access)Radboud Univers...

The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression.

Pittman, Alan M
Naranjo, Silvia
Webb, Emily
Broderick, Peter
Lips, Esther H
van Wezel, Tom
Morreau, Hans
Sullivan, Kate
Fielding, Sarah
Twiss, Philip
Vijayakrishnan, Jayaram
Casares, Fernando
Qureshi, Mobshra
Gómez-Skarmeta, José Luis
Houlston, Richard S

January 2009

Recent genome-wide scans for colorectal cancer (CRC) have revealed the SMAD7 (mothers against decape...

Genetic polymorphism in UDP-glucuronosyltransferase 2B7 and colorectal cancer risk.

Logt, E.M.J. van der
Morsche, R.H.M. te
Groenendaal, N.
Roelofs, H.M.J.
Metz, M. de
Stappen, J.W. van der
Nagengast, F.M.
Peters, W.H.M.

January 2009

Item does not contain fulltextColorectal cancer (CRC) is one of the most common malignancies in the ...

Regulatory cytokine gene polymorphisms and risk of colorectal carcinoma

A. Crivello
A. Giacalone
M. Vaglica
L. Scola
G.I. Forte
M.C. Macaluso
C. Raimondi
L. Di Noto
A. Bongiovanni
A. Accardo
G. Candore
L. Palmeri
Roberto Verna
C. Caruso
D. Lio
S. Palmeri

January 2006

It is well established that cancer arises in chronically inflamed tissue, and this is particularly n...

A Polymorphic Enhancer near GREM1 Influences Bowel Cancer Risk through Differential CDX2 and TCF7L2 Binding

Lewis, Annabelle
Freeman-Mills, Luke
de la Calle-Mustienes, Elisa
Giráldez-Pérez, Rosa María
Davis, Hayley
Jaeger, Emma
Becker, Martin
Hubner, Nina C.
Nguyen, Luan N.
Zeron-Medina, Jorge
Bond, Gareth
Stunnenberg, Hendrik G.
Carvajal, Jaime J.
Gomez-Skarmeta, Jose Luis
Leedham, Simon
Tomlinson, Ian

August 2014

SummaryA rare germline duplication upstream of the bone morphogenetic protein antagonist GREM1 cause...

A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding

Calle-Mustienes, Elisa de la
Giráldez-Pérez, Rosa María
Carvajal, Jaime J.
Gómez-Skarmeta, José Luis
Tomlinson, Ian

January 2016

Under a Creative Commons license.-- et al.A rare germline duplication upstream of the bone morphogen...

A polymorphic enhancer near GREM1 influences bowel cancer risk through diifferential CDX2 and TCF7L2 binding

Lewis, A.
Freeman-Mills, L.
de la Calle-Mustienes, E.
Giráldez-Pérez, R.
Davis, H.
Jaeger, E.
Becker, M.
Hubner, N.
Nguyen, L.
Zeron-Medina, J.
Bond, G.
Stunnenberg, H.
Carvajal, J.
Gomez-Skarmeta, J.
Leedham, S.
Tomlinson, I.

January 2014

A rare germline duplication upstream of the bone morphogenetic protein antagonist GREM1 causes a Men...

A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding.

Lewis, A
Freeman-Mills, L
de la Calle-Mustienes, E
Giráldez-Pérez, RM
Davis, H
Jaeger, E
Becker, M
Hubner, NC
Nguyen, LN
Zeron-Medina, J
Bond, G
Stunnenberg, HG
Carvajal, JJ
Gomez-Skarmeta, JL
Leedham, S
Tomlinson, I

August 2014

A rare germline duplication upstream of the bone morphogenetic protein antagonist GREM1 causes a Men...

Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk.

Logt, E.M.J. van der
Bergevoet, S.M.
Roelofs, H.M.J.
Hooijdonk, Z. van
Morsche, R.H.M. te
Wobbes, T.
Kok, J.B. de
Nagengast, F.M.
Peters, W.H.M.

January 2004

Contains fulltext : 58357.pdf (publisher's version ) (Closed access)Colorectal can...

Polymorphisms in the Insulin-Like Growth Factor Axis Are Associated with Gastrointestinal Cancer

Jennie Ong
Jody Salomon
Rene H. M. Te Morsche
Hennie M. J. Roelofs
Ben J. M. Witteman
Polat Dura
Martin Lacko
Wilbert H. M. Peters

September 2016

The following full text is a publisher's version. For additional information about this publica...

The heterogeneity of genetic predisposition to early-onset colorectal cancer

Hahn, M.M.

January 2016

Contains fulltext : 157676.pdf (publisher's version ) (Open Access)Colorectal canc...

The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression

Naranjo, Silvia
Casares, Fernando
Gómez-Skarmeta, José Luis
Houlston, Richard S.

April 2009

7 páginas, 4 figuras, 1 tabla.-- et al.Recent genome-wide scans for colorectal cancer (CRC) have rev...

Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1.

Jaeger, E
Leedham, S
Lewis, A
Segditsas, S
Becker, M
Cuadrado, PR
Davis, H
Kaur, K
Heinimann, K
Howarth, K
East, J
Taylor, J
Thomas, H
Tomlinson, I

June 2012

Hereditary mixed polyposis syndrome (HMPS) is characterized by apparent autosomal dominant inheritan...

Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1

Jaeger, E.
Leedham, S.
Lewis, A.
Segditsas, S.
Becker, M.
Rodenas-Cuadrado, P.
Davis, H.
Kaur, K.
Heinimann, K.
Howarth, K.
East, J.
Taylor, J.
Thomas, H.
Tomlinson, I.

January 2012

Hereditary mixed polyposis syndrome (HMPS) is characterized by apparent autosomal dominant inheritan...

TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions

Verzi, M. P.
Hatzis, P.
Sulahian, R.
Philips, J.
Schuijers, J.
Shin, H.D.
Freed, E.
Lynch, J. P.
Dang, D. T.
Brown, M.
Clevers, H.
Liu, X. S.
Shivdasani, R. A.

January 2010

Surprisingly few pathways signal between cells, raising questions about mechanisms for tissue-specif...

Molecular alterations underlying genetic predisposition to gastrointestinal cancer

Vogelaar, I.P.

January 2015

Contains fulltext : 140189.pdf (publisher's version ) (Open Access)Radboud Univers...

The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression.

Pittman, Alan M
Naranjo, Silvia
Webb, Emily
Broderick, Peter
Lips, Esther H
van Wezel, Tom
Morreau, Hans
Sullivan, Kate
Fielding, Sarah
Twiss, Philip
Vijayakrishnan, Jayaram
Casares, Fernando
Qureshi, Mobshra
Gómez-Skarmeta, José Luis
Houlston, Richard S

January 2009

Recent genome-wide scans for colorectal cancer (CRC) have revealed the SMAD7 (mothers against decape...

Genetic polymorphism in UDP-glucuronosyltransferase 2B7 and colorectal cancer risk.

Logt, E.M.J. van der
Morsche, R.H.M. te
Groenendaal, N.
Roelofs, H.M.J.
Metz, M. de
Stappen, J.W. van der
Nagengast, F.M.
Peters, W.H.M.

January 2009

Item does not contain fulltextColorectal cancer (CRC) is one of the most common malignancies in the ...

Regulatory cytokine gene polymorphisms and risk of colorectal carcinoma

A. Crivello
A. Giacalone
M. Vaglica
L. Scola
G.I. Forte
M.C. Macaluso
C. Raimondi
L. Di Noto
A. Bongiovanni
A. Accardo
G. Candore
L. Palmeri
Roberto Verna
C. Caruso
D. Lio
S. Palmeri

January 2006

It is well established that cancer arises in chronically inflamed tissue, and this is particularly n...

A polymorphic enhancer near grem1 influences bowel cancer risk through differential cdx2 and tcf7l2 binding

Abstract

Extracted data

A polymorphic enhancer near grem1 influences bowel cancer risk through differential cdx2 and tcf7l2 binding

Abstract

Extracted data

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