Comparison of genotyping using pooled DNA samples (allelotyping) and individual genotyping using the affymetrix genome-wide human SNP array 6.0
- Teumer, A. (Alexander)
- Ernst, F.D.J. (Florian)
- Wiechert, M.A.
- Uhr, K. (Katharina)
- Nauck, M.A. (Matthias)
- Petersmann, A. (Astrid)
- Völzke, H. (Henry)
- Völker, U. (Uwe)
- Homuth, G. (Georg)
Publication date
July 2013
DOI Publisher
Springer Science and Business Media LLCAbstract
Background: Genome-wide association studies (GWAS) using array-based genotyping technology are widely used to identify genetic loci associated with complex diseases or other phenotypes. The costs of GWAS projects based on individual genotyping are still comparatively high and increase with the size of study populations. Genotyping using pooled DNA samples, as also being referred as to allelotyping approach, offers an alternative at affordable costs. In the
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