Pharmacogenetics of Drug-Induced QT Interval Prolongation: An Update
- Niemeijer, M.N. (Maartje)
- Berg, M.E. (Marten) van den
- Eijgelsheim, M. (Mark)
- Rijnbeek, P.R. (Peter)
- Stricker, B.H.Ch. (Bruno)
Publication date
October 2015
DOI Publisher
Springer Science and Business Media LLCAbstract
A prolonged QT interval is an important risk factor for ventricular arrhythmias and sudden cardiac death. QT prolongation can be caused by drugs. There are multiple risk factors for drug-induced QT prolongation, including genetic variation. QT prolongation is one of the most common reasons for withdrawal of
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