Influence of dietary fructose on lipid profile and glycaemic control in healthy individuals

Research Doctorate - Doctor of Philosophy (PhD)Acute consumption of fructose (as sole source of energy) modulates plasma lipids and increases hsCRP levels in healthy individuals. However, it appears that under the conditions that we used; dose (50g) and duration (4 weeks), chronic consumption of of fructose does not modulate CVD risk factors in healthy individuals. Furthermore, a small but statistically significant reduction in BMI and BFM following short-term (one week) fructose restriction suggests that future studies of longer duration may have a positive influence on body composition in healthy adults. This is an important area of future research. As fructose is metabolised differently from other sugars, this becomes important in ascertaining the effect of sugar consumption on cardiovascular health [29]. However, fructose when substituted for glucose in isocaloric diets and not consumed as excess energy, may not increase the risk of developing cardio-metabolic disease