International audienceHigh-level modeling languages and standards, such as Simulink, SysML, MARTE and AADL (Architecture Analysis & Design Language), are increasingly adopted in the design of embedded systems so that system-level analysis, verification and validation (V&V) and architecture exploration are carried out as early as possible. This paper presents our main contribution in this aim by considering embedded systems architectural modeling in AADL and functional modeling in Simulink; an original clock-based timing analysis and validation of the overall system is achieved via a formal polychronous/multi-clock model of computation. In order to avoid semantics ambiguities of AADL and Simulink, their features related to real-time and logi...