Thyroid antibodies after surgical treatment in patients with diffuse toxic goiter

Catedra Endocrinologie, USMF “N. Testemiţanu”The study covered 102 patients with diffuse toxic goiter (DTG) and 24 patients with mono-, polinodular toxic goiter (NTG). A permanent remission occurred in 49% of the patients with DTG and in 28% of the patients with NTG receiving thyrostatic therapy. The risc factors of recurrent toxic goiter included young age (under 35 years), a large size of goiter (more than 30 ml), and the absence of a decrease or an increase in the volume of the thyroid during therapy. Recurrent toxic goiter developed as a rule within a year after thyrostatic treatment - in 50% of the patients with DTG and NTG. Studiul cuprinde 102 pacienţi cu guşă difuză toxică (GDT) şi 24 pacienţi cu guşă uni-, polinodulară toxică (GNT). Remisia permanentă s-a dezvoltat la 49% pacienţi cu GDT şi la 28% pacienţi cu GNT care au primit tratament tireostatic. Factorii de risc ai recidivării guşii toxice includ vârsta tânără (sub 35 ani), dimensiune mare a guşii (mai mare de 30 ml) şi lipsa micşorării sau creşterea volumului tiroidei pe fondal de tratament. Recidivarea guşii toxice mai des are loc pe parcursul primului an de la tratamentul tireostatic, - la 50% dintre pacienţii cu GDT şi GNT