Diagnostic and therapeutic peculiarity of children with perinatal hipoxic and traumatic encephalopathy

Cursul Neuropediatrie USMF “Nicolae Testemiţanu”Currently a lot of affirmations confirm the role of neurotrophic factor of the brain (BDNF, FCNT) in the development of ischemic, traumatic and neurodegenerative lesions of the brain. There was appreciated the seric level of BDNF in the study. It was stipulated that the low level of BDNF is a precocious prognostic criterion for important motor retard lesions in children with perinatal hypoxic-ischemic and traumatic lesions. We appreciated the effectiveness of treatment of children with perinatal hypoxic-ischemic and trauma lesions with antihomotoxic drugs. There was stipulated the improvement of psychomotor and seric levels of BDNF’ acquisitions (other paraclinical investigations) in the dynamics of treatment of children with various neurological syndromes with antihomotoxic drugs. În prezent multiple afirmări confirmă rolul factorilor neurotrofici al creierului (BDNF, FCNT) în dezvoltarea leziunilor ischemice, traumatice şi neurodegenerative ale creierului. În studiu a fost apreciat nivelul seric al BDNF. S-a stipulat că nivelul scăzut al BDNF reprezintă un criteriu de prognostic precoce de retard motor important la copii cu leziuni perinatale hipoxic-ischemice şi traumatice. S-a aprecieat eficienţa tratamentului cu preparate antihomotoxice la copii cu leziuni perinatale hipoxic-ischemice şi traumatice. S-a stipulat ameliorarea achiziţiilor psihomotorii şi nivelului seric al BDNF (alte investigaţii paraclinice) în dinamica tratamentului cu preparate antihomotoxice la copii cu diferite sindroame neurologice