Visible and extended near-infrared multispectral imaging for skin cancer diagnosis

With the goal of diagnosing skin cancer in an early and noninvasive way, an extended near infrared multispectral imaging system based on an InGaAs sensor with sensitivity from 995 nm to 1613 nm was built to evaluate deeper skin layers thanks to the higher penetration of photons at these wavelengths. The outcomes of this device were combined with those of a previously developed multispectral system that works in the visible and near infrared range (414 nm–995 nm). Both provide spectral and spatial information from skin lesions. A classification method to discriminate between melanomas and nevi was developed based on the analysis of first-order statistics descriptors, principal component analysis, and support vector machine tools. The system provided a sensitivity of 78.6% and a specificity of 84.6%, the latter one being improved with respect to that offered by silicon sensors.This research was supported by the Spanish Ministry of Economy and Competitiveness under the grant DPI2014-56850-R, DPI2017-89414-R, and by the European Union through the project DIAGNOPTICS ‘diagnosis of skin cancer using optics’ (ICT PSP seventh call for proposals 2013).Peer ReviewedPostprint (published version