Aristotle holds that some of the predicates that are true of a subject, signify what the subject is. The definition that states what a subject is, is composed out of such predicates, and signifies the essence or nature of the subject. I examine the grounds for distinguishing these predicates in Aristotle's works and I focus on the case of living kinds. In the first part I consider Aristotle's logical works, where the distinction rests on priority relations that relate to explanatory considerations. Given the subjects of a domain or genus studied by a science the predicates that are explanatorily more basic form the essence of those subjects. The aim of scientific understanding is to study the explanatory patterns within a genus; patt...