This thesis investigates why some patients with duodenal ulcer do not respond to blockade and how these patients should be treated. Part 1 examines the effect of cimetidi.'ne lg/day, cimetidine 2g/day and vagotomy on nocturnal gastric secretion in nonresponders. Cimetidine in either dose had no significant effect on volume of gastric secretion but nocturnal intragastric acidity did show a significant decrease. Vagotomy significantly decreased both volume and acidity of secretion. These findings suggest that nonresponse to cimetidine may be due to increased vagal drive. Part 2 investigates vagal function further by measuring nocturnal pepsin secretion in patients receiving cimetidine and ranitidine. Both H2~receptor antagonists in...
Some ill. mountedBibliography: leaves 179-232x, 232, [53] leavesThesis (M.D.) -- University of Adela...
Cimetidine versus ranitidine in short term healing of duodenal ulcers SIR,-Quatrini et al (Giat 1984...
It is now becoming common practice to co-administer H2 receptor antagonists and anti-reflux agents i...
SUMMARY The inhibitory effect of ranitidine and cimetidine on pentagastrin stimulated volume, acid a...
SUMMARY Gastric acid secretion, gastric emptying, fasting serum gastrin and the serum gastrin respon...
SUMMARY The effect of cimetidine, a new histamine H2-receptor antagonist, on gastric acid secretion ...
A multicentre maintenance trial was conducted in 63 peptic ulcer patients to investigate the efficac...
One hundred twenty-one consecutive patients with healed duodenal ulcer (DU) entered a single-blind, ...
A prospective double-blind trial was undertaken to determine whether treatment with cimetidine influ...
The resultsofa double-blind study comparingoral cimetidine withplaceboin the short-term treatment of...
Both meal-stimulated and nocturnal acid secretions have been shown to be abnormally increased in pat...
BACKGROUND: Because of their tolerance and safety, low doses of H2-receptor antagonists are now inc...
Comparison of cimetidine and placebo in the preven-tion of recurrence of ulceration was carried out ...
The Hz-receptor antagonist, cimetidine, profoundly inhibits gastric acid secretion and is effectivel...
SUMMARY The histamine H2-receptor antagonist, cimetidine, when given topically or parenterally, did ...
Some ill. mountedBibliography: leaves 179-232x, 232, [53] leavesThesis (M.D.) -- University of Adela...
Cimetidine versus ranitidine in short term healing of duodenal ulcers SIR,-Quatrini et al (Giat 1984...
It is now becoming common practice to co-administer H2 receptor antagonists and anti-reflux agents i...
SUMMARY The inhibitory effect of ranitidine and cimetidine on pentagastrin stimulated volume, acid a...
SUMMARY Gastric acid secretion, gastric emptying, fasting serum gastrin and the serum gastrin respon...
SUMMARY The effect of cimetidine, a new histamine H2-receptor antagonist, on gastric acid secretion ...
A multicentre maintenance trial was conducted in 63 peptic ulcer patients to investigate the efficac...
One hundred twenty-one consecutive patients with healed duodenal ulcer (DU) entered a single-blind, ...
A prospective double-blind trial was undertaken to determine whether treatment with cimetidine influ...
The resultsofa double-blind study comparingoral cimetidine withplaceboin the short-term treatment of...
Both meal-stimulated and nocturnal acid secretions have been shown to be abnormally increased in pat...
BACKGROUND: Because of their tolerance and safety, low doses of H2-receptor antagonists are now inc...
Comparison of cimetidine and placebo in the preven-tion of recurrence of ulceration was carried out ...
The Hz-receptor antagonist, cimetidine, profoundly inhibits gastric acid secretion and is effectivel...
SUMMARY The histamine H2-receptor antagonist, cimetidine, when given topically or parenterally, did ...
Some ill. mountedBibliography: leaves 179-232x, 232, [53] leavesThesis (M.D.) -- University of Adela...
Cimetidine versus ranitidine in short term healing of duodenal ulcers SIR,-Quatrini et al (Giat 1984...
It is now becoming common practice to co-administer H2 receptor antagonists and anti-reflux agents i...